| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| YES1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates activity | 23245941 | SIGNOR-278248 |
| YES1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates activity | 35041461 | SIGNOR-277653 |
| FRK | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation down-regulates quantity by destabilization | 35723276 | SIGNOR-275456 |
| ABL1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates | 18280240 | SIGNOR-160860 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| YES1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 23245941 | SIGNOR-278248 |
| YES1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 35041461 | SIGNOR-277653 |
| FRK | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation down-regulates ⊣ | YAP1 | 35723276 | SIGNOR-275456 |
| ABL1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 18280240 | SIGNOR-160860 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| YES1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-278248 |
| YES1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277653 |
| FRK | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-275456 |
| ABL1 | phosphorylation → up-regulates | YAP1 | SIGNOR-160860 |
