Entity Details

Name NEK2_Thr143
ID P46937
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
NEK2YAP1Thr143AVSPGTLtPTGVVSGphosphorylation
up-regulates quantity by stabilization		35705994SIGNOR-276586
CDK1YAP1Thr143AVSPGTLtPTGVVSGphosphorylation
up-regulates activity		26933062SIGNOR-276588
CyclinB/CDK1YAP1Thr143AVSPGTLtPTGVVSGphosphorylation
up-regulates activity		26933062SIGNOR-276591
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
NEK2phosphorylation
up-regulates
→
YAP1
PThr143		phosphorylation
up-regulates
→		YAP135705994SIGNOR-276586
CDK1phosphorylation
up-regulates
→
YAP1
PThr143		phosphorylation
up-regulates
→		YAP126933062SIGNOR-276588
CyclinB/CDK1phosphorylation
up-regulates
→
YAP1
PThr143		phosphorylation
up-regulates
→		YAP126933062SIGNOR-276591
Regulator Mechanism/Effect Target SIGNOR-ID
NEK2phosphorylation
→
up-regulates quantity by stabilization 		YAP1SIGNOR-276586
CDK1phosphorylation
→
up-regulates activity 		YAP1SIGNOR-276588
CyclinB/CDK1phosphorylation
→
up-regulates activity 		YAP1SIGNOR-276591