| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| OGT | YAP1 | Ser109 | KSHSRQAsTDAGTAG | glycosylation up-regulates activity | 34155345 | SIGNOR-276942 |
| PRKCZ | YAP1 | Ser109 | KSHSRQAsTDAGTAG | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276876 |
| STK38 | YAP1 | Ser109 | KSHSRQAsTDAGTAG | phosphorylation down-regulates activity | 25601544 | SIGNOR-259856 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| OGT | glycosylation ⊣ | YAP1 PSer109 | glycosylation ⊣ | YAP1 | 34155345 | SIGNOR-276942 |
| PRKCZ | phosphorylation up-regulates → | YAP1 PSer109 | phosphorylation down-regulates ⊣ | YAP1 | 25660024 | SIGNOR-276876 |
| STK38 | phosphorylation up-regulates → | YAP1 PSer109 | phosphorylation down-regulates ⊣ | YAP1 | 25601544 | SIGNOR-259856 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| OGT | glycosylation → up-regulates activity | YAP1 | SIGNOR-276942 |
| PRKCZ | phosphorylation![]() down-regulates quantity by destabilization | YAP1 | SIGNOR-276876 |
| STK38 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-259856 |