Entity Details

Name YES1_Tyr391
ID P46937
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
YES1YAP1Tyr391PFLNSGTyHSRDESTphosphorylation
up-regulates activity		35041461SIGNOR-277652
FRKYAP1Tyr391PFLNSGTyHSRDESTphosphorylation
down-regulates quantity by destabilization		35723276SIGNOR-275455
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
YES1phosphorylation
up-regulates
→
YAP1
PTyr391		phosphorylation
up-regulates
→		YAP135041461SIGNOR-277652
FRKphosphorylation
up-regulates
→
YAP1
PTyr391		phosphorylation
down-regulates
⊣		YAP135723276SIGNOR-275455
Regulator Mechanism/Effect Target SIGNOR-ID
YES1phosphorylation
→
up-regulates activity 		YAP1SIGNOR-277652
FRKphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		YAP1SIGNOR-275455