| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | IQGAP1 | Ser1443 | DKMKKSKsVKEDSNL | phosphorylation up-regulates | 15695813 | SIGNOR-133865 |
| PRKCE | IQGAP1 | Ser1443 | DKMKKSKsVKEDSNL | phosphorylation up-regulates | 15355962 | SIGNOR-128718 |
| PRKCA | IQGAP1 | Ser1443 | DKMKKSKsVKEDSNL | phosphorylation up-regulates | 15695813 | SIGNOR-133861 |
| PRKCA | IQGAP1 | Ser1443 | DKMKKSKsVKEDSNL | phosphorylation up-regulates | 15355962 | SIGNOR-128714 |
| PRKCA | IQGAP1 | Ser1443 | DKMKKSKsVKEDSNL | phosphorylation up-regulates | 21349850 | SIGNOR-172235 |
| PRKCE | IQGAP1 | Ser1443 | DKMKKSKsVKEDSNL | phosphorylation up-regulates | 21349850 | SIGNOR-172239 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | phosphorylation up-regulates → | IQGAP1 PSer1443 | phosphorylation up-regulates → | IQGAP1 | 15695813 | SIGNOR-133865 |
| PRKCE | phosphorylation up-regulates → | IQGAP1 PSer1443 | phosphorylation up-regulates → | IQGAP1 | 15355962 | SIGNOR-128718 |
| PRKCA | phosphorylation up-regulates → | IQGAP1 PSer1443 | phosphorylation up-regulates → | IQGAP1 | 15695813 | SIGNOR-133861 |
| PRKCA | phosphorylation up-regulates → | IQGAP1 PSer1443 | phosphorylation up-regulates → | IQGAP1 | 15355962 | SIGNOR-128714 |
| PRKCA | phosphorylation up-regulates → | IQGAP1 PSer1443 | phosphorylation up-regulates → | IQGAP1 | 21349850 | SIGNOR-172235 |
| PRKCE | phosphorylation up-regulates → | IQGAP1 PSer1443 | phosphorylation up-regulates → | IQGAP1 | 21349850 | SIGNOR-172239 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCE | phosphorylation → up-regulates | IQGAP1 | SIGNOR-133865 |
| PRKCE | phosphorylation → up-regulates | IQGAP1 | SIGNOR-128718 |
| PRKCA | phosphorylation → up-regulates | IQGAP1 | SIGNOR-133861 |
| PRKCA | phosphorylation → up-regulates | IQGAP1 | SIGNOR-128714 |
| PRKCA | phosphorylation → up-regulates | IQGAP1 | SIGNOR-172235 |
| PRKCE | phosphorylation → up-regulates | IQGAP1 | SIGNOR-172239 |
