| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | PLA2G4A | Ser505 | LNTSYPLsPLSDFAT | phosphorylation unknown | 9468497 | SIGNOR-55706 |
| MAPK3 | PLA2G4A | Ser505 | LNTSYPLsPLSDFAT | phosphorylation up-regulates | 8381049 | SIGNOR-38434 |
| MAPK14 | PLA2G4A | Ser505 | LNTSYPLsPLSDFAT | phosphorylation up-regulates activity | 8910365 | SIGNOR-44673 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | PLA2G4A PSer505 | phosphorylation down-regulates ⊣ | PLA2G4A | 9468497 | SIGNOR-55706 |
| MAPK3 | phosphorylation up-regulates → | PLA2G4A PSer505 | phosphorylation up-regulates → | PLA2G4A | 8381049 | SIGNOR-38434 |
| MAPK14 | phosphorylation up-regulates → | PLA2G4A PSer505 | phosphorylation up-regulates → | PLA2G4A | 8910365 | SIGNOR-44673 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → unknown | PLA2G4A | SIGNOR-55706 |
| MAPK3 | phosphorylation → up-regulates | PLA2G4A | SIGNOR-38434 |
| MAPK14 | phosphorylation → up-regulates activity | PLA2G4A | SIGNOR-44673 |
