Entity Details

Name KCNJ4
ID P48050
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKAKCNJ4Ser443NISYRREsAIphosphorylation
up-regulates activity		19635485SIGNOR-263153
EGFRKCNJ4Tyr234YMTQEGEyLPLDQRDphosphorylation
up-regulates activity		21486282SIGNOR-276322
PRKCAKCNJ4Thr53IFTTCVDtRWRYMLMphosphorylation
down-regulates activity		10206975SIGNOR-275965
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKAphosphorylation
up-regulates
→
KCNJ4
PSer443		phosphorylation
up-regulates
→		KCNJ419635485SIGNOR-263153
EGFRphosphorylation
up-regulates
→
KCNJ4
PTyr234		phosphorylation
up-regulates
→		KCNJ421486282SIGNOR-276322
PRKCAphosphorylation
up-regulates
→
KCNJ4
PThr53		phosphorylation
down-regulates
⊣		KCNJ410206975SIGNOR-275965
Regulator Mechanism/Effect Target SIGNOR-ID
PKAphosphorylation
→
up-regulates activity 		KCNJ4SIGNOR-263153
EGFRphosphorylation
→
up-regulates activity 		KCNJ4SIGNOR-276322
PRKCAphosphorylation
→
down-regulates activity 		KCNJ4SIGNOR-275965