| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA1 | NR2C2 | Ser351 | HVISRDQsTPIIEVE | phosphorylation down-regulates | 21478464 | SIGNOR-173118 |
| AMPK | NR2C2 | Ser351 | HVISRDQsTPIIEVE | phosphorylation down-regulates | 21478464 | SIGNOR-216537 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA1 | phosphorylation up-regulates → | NR2C2 PSer351 | phosphorylation down-regulates ⊣ | NR2C2 | 21478464 | SIGNOR-173118 |
| AMPK | phosphorylation up-regulates → | NR2C2 PSer351 | phosphorylation down-regulates ⊣ | NR2C2 | 21478464 | SIGNOR-216537 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKAA1 | phosphorylation![]() down-regulates | NR2C2 | SIGNOR-173118 |
| AMPK | phosphorylation![]() down-regulates | NR2C2 | SIGNOR-216537 |