Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
DYRK1A	AMPH	Ser276 View in OncoXplorer	PLPSPTAsPNHTLAP	phosphorylation down-regulates	15262992	SIGNOR-126847
CyclinB/CDK1	AMPH	Ser276 View in OncoXplorer	PLPSPTAsPNHTLAP	phosphorylation unknown	11113134	SIGNOR-250645
CDK5	AMPH	Ser276 View in OncoXplorer	PLPSPTAsPNHTLAP	phosphorylation unknown	11113134	SIGNOR-250649

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
DYRK1A	phosphorylation up-regulates →	AMPH PSer276	phosphorylation down-regulates ⊣	AMPH	15262992	SIGNOR-126847
CyclinB/CDK1	phosphorylation up-regulates →	AMPH PSer276	phosphorylation down-regulates ⊣	AMPH	11113134	SIGNOR-250645
CDK5	phosphorylation up-regulates →	AMPH PSer276	phosphorylation down-regulates ⊣	AMPH	11113134	SIGNOR-250649

Regulator	Mechanism/Effect	Target	SIGNOR-ID
DYRK1A	phosphorylation down-regulates	AMPH	SIGNOR-126847
CyclinB/CDK1	phosphorylation → unknown	AMPH	SIGNOR-250645
CDK5	phosphorylation → unknown	AMPH	SIGNOR-250649