Entity Details

Name MAPK3_Ser293
ID P49418
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDKL5AMPHSer293PAPARPRsPSQTRKGphosphorylation
down-regulates activity		23651931SIGNOR-245881
DYRK1AAMPHSer293PAPARPRsPSQTRKGphosphorylation
down-regulates activity		16733250SIGNOR-146902
MAPK3AMPHSer293PAPARPRsPSQTRKGphosphorylation
down-regulates activity		15262992SIGNOR-126867
MAPK1AMPHSer293PAPARPRsPSQTRKGphosphorylation
down-regulates activity		15262992SIGNOR-126859
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDKL5phosphorylation
up-regulates
→
AMPH
PSer293		phosphorylation
down-regulates
⊣		AMPH23651931SIGNOR-245881
DYRK1Aphosphorylation
up-regulates
→
AMPH
PSer293		phosphorylation
down-regulates
⊣		AMPH16733250SIGNOR-146902
MAPK3phosphorylation
up-regulates
→
AMPH
PSer293		phosphorylation
down-regulates
⊣		AMPH15262992SIGNOR-126867
MAPK1phosphorylation
up-regulates
→
AMPH
PSer293		phosphorylation
down-regulates
⊣		AMPH15262992SIGNOR-126859
Regulator Mechanism/Effect Target SIGNOR-ID
CDKL5phosphorylation
→
down-regulates activity 		AMPHSIGNOR-245881
DYRK1Aphosphorylation
→
down-regulates activity 		AMPHSIGNOR-146902
MAPK3phosphorylation
→
down-regulates activity 		AMPHSIGNOR-126867
MAPK1phosphorylation
→
down-regulates activity 		AMPHSIGNOR-126859