| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | CENPA | Ser68 | LIRKLPFsRLAREIC | phosphorylation down-regulates quantity by destabilization | 34758320 | SIGNOR-277576 |
| AURKB | CENPA | Ser7 | sRKPEAPR | phosphorylation unknown | 11756469 | SIGNOR-250585 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | CENPA PSer68 | phosphorylation down-regulates ⊣ | CENPA | 34758320 | SIGNOR-277576 |
| AURKB | phosphorylation up-regulates → | CENPA PSer7 | phosphorylation down-regulates ⊣ | CENPA | 11756469 | SIGNOR-250585 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation down-regulates quantity by destabilization | CENPA | SIGNOR-277576 |
| AURKB | phosphorylation → unknown | CENPA | SIGNOR-250585 |
