| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | MCM2 | Ser13 | ESFTMASsPAQRRRG | phosphorylation up-regulates | 16446360 | SIGNOR-144000 |
| CSNK2A1 | MCM2 | Ser13 | ESFTMASsPAQRRRG | phosphorylation up-regulates | 16446360 | SIGNOR-144004 |
| CDC7 | MCM2 | Ser13 | ESFTMASsPAQRRRG | phosphorylation up-regulates | 16446360 | SIGNOR-143984 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | MCM2 PSer13 | phosphorylation up-regulates → | MCM2 | 16446360 | SIGNOR-144000 |
| CSNK2A1 | phosphorylation up-regulates → | MCM2 PSer13 | phosphorylation up-regulates → | MCM2 | 16446360 | SIGNOR-144004 |
| CDC7 | phosphorylation up-regulates → | MCM2 PSer13 | phosphorylation up-regulates → | MCM2 | 16446360 | SIGNOR-143984 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation → up-regulates | MCM2 | SIGNOR-144000 |
| CSNK2A1 | phosphorylation → up-regulates | MCM2 | SIGNOR-144004 |
| CDC7 | phosphorylation → up-regulates | MCM2 | SIGNOR-143984 |