| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | MCM2 | Ser108 | DVEELTAsQREAAER | phosphorylation unknown | 15210935 | SIGNOR-126363 |
| CDC7 | MCM2 | Ser108 | DVEELTAsQREAAER | phosphorylation up-regulates | 19647517 | SIGNOR-187388 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | phosphorylation up-regulates → | MCM2 PSer108 | phosphorylation down-regulates ⊣ | MCM2 | 15210935 | SIGNOR-126363 |
| CDC7 | phosphorylation up-regulates → | MCM2 PSer108 | phosphorylation up-regulates → | MCM2 | 19647517 | SIGNOR-187388 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATR | phosphorylation → unknown | MCM2 | SIGNOR-126363 |
| CDC7 | phosphorylation → up-regulates | MCM2 | SIGNOR-187388 |
