Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
AAK1	NUMB	Thr102	LRVVDEKtKDLIVDQ	phosphorylation up-regulates	18657069	SIGNOR-179606
CAMK1	NUMB	Ser276 View in OncoXplorer	EQLARQGsFRGFPAL	phosphorylation down-regulates	17022975	SIGNOR-149993
PRKCI	NUMB	–		phosphorylation down-regulates	17609107	SIGNOR-156765
AAK1	NUMB	Thr102	LRVVDEKtKDLIVDQ	phosphorylation unknown	18657069	SIGNOR-179610

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
AAK1	phosphorylation up-regulates →	NUMB PThr102	phosphorylation up-regulates →	NUMB	18657069	SIGNOR-179606
CAMK1	phosphorylation up-regulates →	NUMB PSer276	phosphorylation down-regulates ⊣	NUMB	17022975	SIGNOR-149993
AAK1	phosphorylation up-regulates →	NUMB PThr102	phosphorylation down-regulates ⊣	NUMB	18657069	SIGNOR-179610

Regulator	Mechanism/Effect	Target	SIGNOR-ID
AAK1	phosphorylation → up-regulates	NUMB	SIGNOR-179606
CAMK1	phosphorylation down-regulates	NUMB	SIGNOR-149993
PRKCI	phosphorylation down-regulates	NUMB	SIGNOR-156765
AAK1	phosphorylation → unknown	NUMB	SIGNOR-179610