Entity Details

Name PSEN1_Ser346
ID P49768
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCGPSEN1Ser346EWEAQRDsHLGPHRSphosphorylation
up-regulates activity		14576165SIGNOR-249238
PRKCZPSEN1Ser346EWEAQRDsHLGPHRSphosphorylation
up-regulates activity		14576165SIGNOR-249239
PRKCBPSEN1Ser346EWEAQRDsHLGPHRSphosphorylation
up-regulates activity		14576165SIGNOR-249237
PRKCAPSEN1Ser346EWEAQRDsHLGPHRSphosphorylation
up-regulates activity		14576165SIGNOR-249236
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCGphosphorylation
up-regulates
→
PSEN1
PSer346		phosphorylation
up-regulates
→		PSEN114576165SIGNOR-249238
PRKCZphosphorylation
up-regulates
→
PSEN1
PSer346		phosphorylation
up-regulates
→		PSEN114576165SIGNOR-249239
PRKCBphosphorylation
up-regulates
→
PSEN1
PSer346		phosphorylation
up-regulates
→		PSEN114576165SIGNOR-249237
PRKCAphosphorylation
up-regulates
→
PSEN1
PSer346		phosphorylation
up-regulates
→		PSEN114576165SIGNOR-249236
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCGphosphorylation
→
up-regulates activity 		PSEN1SIGNOR-249238
PRKCZphosphorylation
→
up-regulates activity 		PSEN1SIGNOR-249239
PRKCBphosphorylation
→
up-regulates activity 		PSEN1SIGNOR-249237
PRKCAphosphorylation
→
up-regulates activity 		PSEN1SIGNOR-249236