| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1D | PSEN2 | Ser19 | EVCDERTsLMSAESP | phosphorylation unknown | 8972483 | SIGNOR-250799 |
| CSNK1A1 | PSEN2 | Ser19 | EVCDERTsLMSAESP | phosphorylation unknown | 8972483 | SIGNOR-250790 |
| CSNK2A1 | PSEN2 | Ser19 | EVCDERTsLMSAESP | phosphorylation unknown | 8972483 | SIGNOR-250932 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1D | phosphorylation up-regulates → | PSEN2 PSer19 | phosphorylation down-regulates ⊣ | PSEN2 | 8972483 | SIGNOR-250799 |
| CSNK1A1 | phosphorylation up-regulates → | PSEN2 PSer19 | phosphorylation down-regulates ⊣ | PSEN2 | 8972483 | SIGNOR-250790 |
| CSNK2A1 | phosphorylation up-regulates → | PSEN2 PSer19 | phosphorylation down-regulates ⊣ | PSEN2 | 8972483 | SIGNOR-250932 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK1D | phosphorylation → unknown | PSEN2 | SIGNOR-250799 |
| CSNK1A1 | phosphorylation → unknown | PSEN2 | SIGNOR-250790 |
| CSNK2A1 | phosphorylation → unknown | PSEN2 | SIGNOR-250932 |
