| Name | GSK3A |
| ID | P49840 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 119-403 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | MAFA | Thr53 | PPGSLSStPLSTPCS | phosphorylation up-regulates activity | 18042454 | SIGNOR-159373 |
| GSK3A | ARHGAP31 | Thr789 | PPAPPPPtPLEESTP | phosphorylation up-regulates activity | 17158447 | SIGNOR-262878 |
| GSK3A | BCL3 | Ser406 | PSSSPSQsPPRDPPG | phosphorylation down-regulates quantity by destabilization | 15469820 | SIGNOR-276012 |
| GSK3A | AKT | Thr312 | TMKTFCGtPEYLAPE | phosphorylation down-regulates activity | 23142783 | SIGNOR-252455 |
| GSK3A | MAFA | Thr53 | PPGSLSStPLSTPCS | phosphorylation down-regulates quantity by destabilization | 18042454 | SIGNOR-159394 |
| GSK3A | UNG | Thr60 | AGQEEPGtPPSSPLS | phosphorylation down-regulates quantity by destabilization | 27875297 | SIGNOR-264887 |
| GSK3A | TSC2 | – | phosphorylation up-regulates | 20226003 | SIGNOR-164098 | |
| GSK3A | GATA6 | Ser37 | REPSTPPsPISSSSS | phosphorylation down-regulates quantity by destabilization | 27273097 | SIGNOR-253156 |
| GSK3A | STMN3 | Ser60 | SFEVILKsPSDLSPE | phosphorylation up-regulates activity | 22577147 | SIGNOR-264883 |
| GSK3A | NOL3 | – | phosphorylation down-regulates quantity by destabilization | 28670266 | SIGNOR-279179 | |
| GSK3A | JUN | – | phosphorylation down-regulates | 16023596 | SIGNOR-138592 | |
| GSK3A | STAT2 | Ser381 | RKFNILTsNQKTLTP | phosphorylation down-regulates quantity by destabilization | 31843895 | SIGNOR-276760 |
| GSK3A | PPARA | Ser280 | FHCCQCTsVETVTEL | phosphorylation up-regulates activity | 30745182 | SIGNOR-278515 |
| GSK3A | NBR1 | Thr586 | HNTPVDVtPCMSPLP | phosphorylation down-regulates activity | 24879152 | SIGNOR-261794 |
| GSK3A | GRB14 | Ser362 | QGRSGCSsQSISPMR | phosphorylation down-regulates activity | 28130417 | SIGNOR-264870 |
| GSK3A | UNG | Ser64 | EPGTPPSsPLSAEQL | phosphorylation down-regulates quantity by destabilization | 27875297 | SIGNOR-264886 |
| GSK3A | GSK3A | Tyr279 | RGEPNVSyICSRYYR | phosphorylation up-regulates | 18701488 | SIGNOR-180035 |
| GSK3A | FCAR | Ser284 | LTFARTPsVCK | phosphorylation down-regulates activity | 30766540 | SIGNOR-264856 |
| GSK3A | NEFH | – | phosphorylation down-regulates activity | 8627328 | SIGNOR-279783 | |
| GSK3A | CAMKK2 | Ser133 | LPYSPVSsPQSSPRL | phosphorylation down-regulates | 22778263 | SIGNOR-198126 |
| GSK3A | STAT2 | Ser393 | LTPEKGQsQGLIWDF | phosphorylation down-regulates quantity by destabilization | 31843895 | SIGNOR-276762 |
| GSK3A | STAT2 | Thr385 | ILTSNQKtLTPEKGQ | phosphorylation down-regulates quantity by destabilization | 31843895 | SIGNOR-276761 |
| GSK3A | NIFK | Thr234 | TVDSQGPtPVCTPTF | phosphorylation up-regulates activity | 16244663 | SIGNOR-262697 |
| GSK3A | JUN | Thr239 | VPEMPGEtPPLSPID | phosphorylation down-regulates | 1846781 | SIGNOR-21784 |
| GSK3A | SFPQ | Thr687 | PRGMGPGtPAGYGRG | phosphorylation down-regulates | 20932480 | SIGNOR-168382 |
| GSK3A | RICTOR | Thr1695 | EAEAVLAtPPKQPIV | phosphorylation down-regulates quantity by destabilization | 25897075 | SIGNOR-276899 |
| GSK3A | GRB14 | Ser366 | GCSSQSIsPMRSISE | phosphorylation down-regulates activity | 28130417 | SIGNOR-264872 |
| GSK3A | CAMKK2 | Ser137 | PVSSPQSsPRLPRRP | phosphorylation down-regulates | 22778263 | SIGNOR-198130 |
| GSK3A | JUN | Ser249 | LSPIDMEsQERIKAE | phosphorylation down-regulates | 1846781 | SIGNOR-21780 |
| GSK3A | MAPT | Ser641 | KVTSKCGsLGNIHHK | phosphorylation down-regulates activity | 7706316 | SIGNOR-249342 |
| GSK3A | MAFA | Ser61 | PLSTPCSsVPSSPSF | phosphorylation up-regulates activity | 18042454 | SIGNOR-159369 |
| GSK3A | GRB14 | Ser358 | MHPYQGRsGCSSQSI | phosphorylation down-regulates activity | 28130417 | SIGNOR-264871 |
| GSK3A | CD274 | Ser279 | CGIQDTNsKKQSDTH | phosphorylation down-regulates quantity by destabilization | 33879767 | SIGNOR-277552 |
| GSK3A | GPSM3 | Ser35 | STTRPWRsAPPSPPP | phosphorylation down-regulates quantity by destabilization | 22843681 | SIGNOR-264863 |
| GSK3A | MAF | – | phosphorylation down-regulates | 18042454 | SIGNOR-159361 | |
| GSK3A | MITF | Ser405 | QARAHGLsLIPSTGL | phosphorylation up-regulates | 10587587 | SIGNOR-72878 |
| GSK3A | CAMKK2 | Ser129 | ICPSLPYsPVSSPQS | phosphorylation down-regulates | 22778263 | SIGNOR-198122 |
| GSK3A | MAFA | Ser49 | CHRLPPGsLSSTPLS | phosphorylation down-regulates quantity by destabilization | 18042454 | SIGNOR-159381 |
| GSK3A | RELA | Thr254 | RQVAIVFRtPPYADPS | phosphorylation up-regulates activity | 22761446 | SIGNOR-255827 |
| GSK3A | MAFA | Thr57 | LSSTPLStPCSSVPS | phosphorylation down-regulates quantity by destabilization | 18042454 | SIGNOR-159398 |
| GSK3A | BCL3 | Ser402 | LSASPSSsPSQSPPR | phosphorylation down-regulates quantity by destabilization | 15469820 | SIGNOR-276011 |
| GSK3A | NCOA3 | Ser509 | GVHSPMAsSGNTGNH | phosphorylation down-regulates quantity by destabilization | 17574025 | SIGNOR-276067 |
| GSK3A | OSBP2 | – | phosphorylation up-regulates activity | 30925160 | SIGNOR-264875 | |
| GSK3A | MAFA | Ser61 | PLSTPCSsVPSSPSF | phosphorylation down-regulates quantity by destabilization | 18042454 | SIGNOR-159390 |
| GSK3A | PPARA | Ser280 | FHCCQCTsVETVTEL | phosphorylation up-regulates activity | 30745182 | SIGNOR-277431 |
| GSK3A | MAFA | Ser49 | CHRLPPGsLSSTPLS | phosphorylation up-regulates activity | 18042454 | SIGNOR-159365 |
| GSK3A | PKD2 | Ser76 | AGAAASPsPPLSSCS | phosphorylation unknown | 16551655 | SIGNOR-145306 |
| GSK3A | NOTCH1 | – | phosphorylation down-regulates | 19214430 | SIGNOR-183969 | |
| GSK3A | EIF2B5 | Ser540 | MDSEEPDsRGGSPQM | phosphorylation down-regulates activity | 11500362 | SIGNOR-251215 |
| GSK3A | JUN | Ser243 | PGETPPLsPIDMESQ | phosphorylation down-regulates | 1846781 | SIGNOR-21776 |
| GSK3A | MCL1 | Ser159 | NNTSTDGsLPSTPPP | phosphorylation down-regulates quantity by destabilization | 16543145 | SIGNOR-251217 |
| GSK3A | IL17RA | Thr780 | MVLTDPHtPYEEEQR | phosphorylation down-regulates quantity by destabilization | 26871944 | SIGNOR-277206 |
| GSK3A | SFPQ | – | phosphorylation down-regulates | 20932480 | SIGNOR-168385 | |
| GSK3A | MAF | – | phosphorylation up-regulates | 18042454 | SIGNOR-159358 | |
| GSK3A | LRP6 | Ser1490 | AILNPPPsPATERSH | phosphorylation up-regulates activity | 35487243 | SIGNOR-275398 |
| GSK3A | MAFA | Thr57 | LSSTPLStPCSSVPS | phosphorylation up-regulates activity | 18042454 | SIGNOR-159377 |
| GSK3A | ANKRD28 | Ser1007 | INRYTNTsKTVSFEA | phosphorylation down-regulates activity | 17023142 | SIGNOR-264792 |
| GSK3A | GYS1 | Ser641 | YRYPRPAsVPPSPSL | phosphorylation down-regulates | 14593110 | SIGNOR-118927 |
| GSK3A | TSC2 | – | phosphorylation up-regulates | 16959574 | SIGNOR-149377 | |
| GSK3A | MAPT | Ser579 | NVKSKIGsTENLKHQ | phosphorylation down-regulates | 9771888 | SIGNOR-60651 |
| GSK3A | MAPT | – | phosphorylation down-regulates | 7566348 | SIGNOR-29364 | |
| GSK3A | MAFB | – | phosphorylation down-regulates | 18042454 | SIGNOR-159432 | |
| GSK3A | MYC | Thr58 | KKFELLPtPPLSPSR | phosphorylation down-regulates quantity by destabilization | 16023596 | SIGNOR-138596 |
| GSK3A | AKT1 | Thr312 | TMKTFCGtPEYLAPE | phosphorylation down-regulates activity | 23142783 | SIGNOR-252434 |
| GSK3A | MAFB | – | phosphorylation up-regulates | 18042454 | SIGNOR-159429 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | phosphorylation up-regulates → | MAFA PThr53 | phosphorylation up-regulates → | MAFA | 18042454 | SIGNOR-159373 |
| GSK3A | phosphorylation up-regulates → | ARHGAP31 PThr789 | phosphorylation up-regulates → | ARHGAP31 | 17158447 | SIGNOR-262878 |
| GSK3A | phosphorylation up-regulates → | BCL3 PSer406 | phosphorylation down-regulates ⊣ | BCL3 | 15469820 | SIGNOR-276012 |
| GSK3A | phosphorylation up-regulates → | AKT PThr312 | phosphorylation down-regulates ⊣ | AKT | 23142783 | SIGNOR-252455 |
| GSK3A | phosphorylation up-regulates → | MAFA PThr53 | phosphorylation down-regulates ⊣ | MAFA | 18042454 | SIGNOR-159394 |
| GSK3A | phosphorylation up-regulates → | UNG PThr60 | phosphorylation down-regulates ⊣ | UNG | 27875297 | SIGNOR-264887 |
| GSK3A | phosphorylation up-regulates → | GATA6 PSer37 | phosphorylation down-regulates ⊣ | GATA6 | 27273097 | SIGNOR-253156 |
| GSK3A | phosphorylation up-regulates → | STMN3 PSer60 | phosphorylation up-regulates → | STMN3 | 22577147 | SIGNOR-264883 |
| GSK3A | phosphorylation up-regulates → | STAT2 PSer381 | phosphorylation down-regulates ⊣ | STAT2 | 31843895 | SIGNOR-276760 |
| GSK3A | phosphorylation up-regulates → | PPARA PSer280 | phosphorylation up-regulates → | PPARA | 30745182 | SIGNOR-278515 |
| GSK3A | phosphorylation up-regulates → | NBR1 PThr586 | phosphorylation down-regulates ⊣ | NBR1 | 24879152 | SIGNOR-261794 |
| GSK3A | phosphorylation up-regulates → | GRB14 PSer362 | phosphorylation down-regulates ⊣ | GRB14 | 28130417 | SIGNOR-264870 |
| GSK3A | phosphorylation up-regulates → | UNG PSer64 | phosphorylation down-regulates ⊣ | UNG | 27875297 | SIGNOR-264886 |
| GSK3A | phosphorylation up-regulates → | GSK3A PTyr279 | phosphorylation up-regulates → | GSK3A | 18701488 | SIGNOR-180035 |
| GSK3A | phosphorylation up-regulates → | FCAR PSer284 | phosphorylation down-regulates ⊣ | FCAR | 30766540 | SIGNOR-264856 |
| GSK3A | phosphorylation up-regulates → | CAMKK2 PSer133 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-198126 |
| GSK3A | phosphorylation up-regulates → | STAT2 PSer393 | phosphorylation down-regulates ⊣ | STAT2 | 31843895 | SIGNOR-276762 |
| GSK3A | phosphorylation up-regulates → | STAT2 PThr385 | phosphorylation down-regulates ⊣ | STAT2 | 31843895 | SIGNOR-276761 |
| GSK3A | phosphorylation up-regulates → | NIFK PThr234 | phosphorylation up-regulates → | NIFK | 16244663 | SIGNOR-262697 |
| GSK3A | phosphorylation up-regulates → | JUN PThr239 | phosphorylation down-regulates ⊣ | JUN | 1846781 | SIGNOR-21784 |
| GSK3A | phosphorylation up-regulates → | SFPQ PThr687 | phosphorylation down-regulates ⊣ | SFPQ | 20932480 | SIGNOR-168382 |
| GSK3A | phosphorylation up-regulates → | RICTOR PThr1695 | phosphorylation down-regulates ⊣ | RICTOR | 25897075 | SIGNOR-276899 |
| GSK3A | phosphorylation up-regulates → | GRB14 PSer366 | phosphorylation down-regulates ⊣ | GRB14 | 28130417 | SIGNOR-264872 |
| GSK3A | phosphorylation up-regulates → | CAMKK2 PSer137 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-198130 |
| GSK3A | phosphorylation up-regulates → | JUN PSer249 | phosphorylation down-regulates ⊣ | JUN | 1846781 | SIGNOR-21780 |
| GSK3A | phosphorylation up-regulates → | MAPT PSer641 | phosphorylation down-regulates ⊣ | MAPT | 7706316 | SIGNOR-249342 |
| GSK3A | phosphorylation up-regulates → | MAFA PSer61 | phosphorylation up-regulates → | MAFA | 18042454 | SIGNOR-159369 |
| GSK3A | phosphorylation up-regulates → | GRB14 PSer358 | phosphorylation down-regulates ⊣ | GRB14 | 28130417 | SIGNOR-264871 |
| GSK3A | phosphorylation up-regulates → | CD274 PSer279 | phosphorylation down-regulates ⊣ | CD274 | 33879767 | SIGNOR-277552 |
| GSK3A | phosphorylation up-regulates → | GPSM3 PSer35 | phosphorylation down-regulates ⊣ | GPSM3 | 22843681 | SIGNOR-264863 |
| GSK3A | phosphorylation up-regulates → | MITF PSer405 | phosphorylation up-regulates → | MITF | 10587587 | SIGNOR-72878 |
| GSK3A | phosphorylation up-regulates → | CAMKK2 PSer129 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-198122 |
| GSK3A | phosphorylation up-regulates → | MAFA PSer49 | phosphorylation down-regulates ⊣ | MAFA | 18042454 | SIGNOR-159381 |
| GSK3A | phosphorylation up-regulates → | RELA PThr254 | phosphorylation up-regulates → | RELA | 22761446 | SIGNOR-255827 |
| GSK3A | phosphorylation up-regulates → | MAFA PThr57 | phosphorylation down-regulates ⊣ | MAFA | 18042454 | SIGNOR-159398 |
| GSK3A | phosphorylation up-regulates → | BCL3 PSer402 | phosphorylation down-regulates ⊣ | BCL3 | 15469820 | SIGNOR-276011 |
| GSK3A | phosphorylation up-regulates → | NCOA3 PSer509 | phosphorylation down-regulates ⊣ | NCOA3 | 17574025 | SIGNOR-276067 |
| GSK3A | phosphorylation up-regulates → | MAFA PSer61 | phosphorylation down-regulates ⊣ | MAFA | 18042454 | SIGNOR-159390 |
| GSK3A | phosphorylation up-regulates → | PPARA PSer280 | phosphorylation up-regulates → | PPARA | 30745182 | SIGNOR-277431 |
| GSK3A | phosphorylation up-regulates → | MAFA PSer49 | phosphorylation up-regulates → | MAFA | 18042454 | SIGNOR-159365 |
| GSK3A | phosphorylation up-regulates → | PKD2 PSer76 | phosphorylation down-regulates ⊣ | PKD2 | 16551655 | SIGNOR-145306 |
| GSK3A | phosphorylation up-regulates → | EIF2B5 PSer540 | phosphorylation down-regulates ⊣ | EIF2B5 | 11500362 | SIGNOR-251215 |
| GSK3A | phosphorylation up-regulates → | JUN PSer243 | phosphorylation down-regulates ⊣ | JUN | 1846781 | SIGNOR-21776 |
| GSK3A | phosphorylation up-regulates → | MCL1 PSer159 | phosphorylation down-regulates ⊣ | MCL1 | 16543145 | SIGNOR-251217 |
| GSK3A | phosphorylation up-regulates → | IL17RA PThr780 | phosphorylation down-regulates ⊣ | IL17RA | 26871944 | SIGNOR-277206 |
| GSK3A | phosphorylation up-regulates → | LRP6 PSer1490 | phosphorylation up-regulates → | LRP6 | 35487243 | SIGNOR-275398 |
| GSK3A | phosphorylation up-regulates → | MAFA PThr57 | phosphorylation up-regulates → | MAFA | 18042454 | SIGNOR-159377 |
| GSK3A | phosphorylation up-regulates → | ANKRD28 PSer1007 | phosphorylation down-regulates ⊣ | ANKRD28 | 17023142 | SIGNOR-264792 |
| GSK3A | phosphorylation up-regulates → | GYS1 PSer641 | phosphorylation down-regulates ⊣ | GYS1 | 14593110 | SIGNOR-118927 |
| GSK3A | phosphorylation up-regulates → | MAPT PSer579 | phosphorylation down-regulates ⊣ | MAPT | 9771888 | SIGNOR-60651 |
| GSK3A | phosphorylation up-regulates → | MYC PThr58 | phosphorylation down-regulates ⊣ | MYC | 16023596 | SIGNOR-138596 |
| GSK3A | phosphorylation up-regulates → | AKT1 PThr312 | phosphorylation down-regulates ⊣ | AKT1 | 23142783 | SIGNOR-252434 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3A | phosphorylation → up-regulates activity | MAFA | SIGNOR-159373 |
| GSK3A | phosphorylation → up-regulates activity | ARHGAP31 | SIGNOR-262878 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | BCL3 | SIGNOR-276012 |
| GSK3A | phosphorylation → down-regulates activity | AKT | SIGNOR-252455 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | MAFA | SIGNOR-159394 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | UNG | SIGNOR-264887 |
| GSK3A | phosphorylation → up-regulates | TSC2 | SIGNOR-164098 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | GATA6 | SIGNOR-253156 |
| GSK3A | phosphorylation → up-regulates activity | STMN3 | SIGNOR-264883 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | NOL3 | SIGNOR-279179 |
| GSK3A | phosphorylation down-regulates | JUN | SIGNOR-138592 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | STAT2 | SIGNOR-276760 |
| GSK3A | phosphorylation → up-regulates activity | PPARA | SIGNOR-278515 |
| GSK3A | phosphorylation → down-regulates activity | NBR1 | SIGNOR-261794 |
| GSK3A | phosphorylation → down-regulates activity | GRB14 | SIGNOR-264870 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | UNG | SIGNOR-264886 |
| GSK3A | phosphorylation → up-regulates | GSK3A | SIGNOR-180035 |
| GSK3A | phosphorylation → down-regulates activity | FCAR | SIGNOR-264856 |
| GSK3A | phosphorylation → down-regulates activity | NEFH | SIGNOR-279783 |
| GSK3A | phosphorylation down-regulates | CAMKK2 | SIGNOR-198126 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | STAT2 | SIGNOR-276762 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | STAT2 | SIGNOR-276761 |
| GSK3A | phosphorylation → up-regulates activity | NIFK | SIGNOR-262697 |
| GSK3A | phosphorylation down-regulates | JUN | SIGNOR-21784 |
| GSK3A | phosphorylation down-regulates | SFPQ | SIGNOR-168382 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | RICTOR | SIGNOR-276899 |
| GSK3A | phosphorylation → down-regulates activity | GRB14 | SIGNOR-264872 |
| GSK3A | phosphorylation down-regulates | CAMKK2 | SIGNOR-198130 |
| GSK3A | phosphorylation down-regulates | JUN | SIGNOR-21780 |
| GSK3A | phosphorylation → down-regulates activity | MAPT | SIGNOR-249342 |
| GSK3A | phosphorylation → up-regulates activity | MAFA | SIGNOR-159369 |
| GSK3A | phosphorylation → down-regulates activity | GRB14 | SIGNOR-264871 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | CD274 | SIGNOR-277552 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | GPSM3 | SIGNOR-264863 |
| GSK3A | phosphorylation down-regulates | MAF | SIGNOR-159361 |
| GSK3A | phosphorylation → up-regulates | MITF | SIGNOR-72878 |
| GSK3A | phosphorylation down-regulates | CAMKK2 | SIGNOR-198122 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | MAFA | SIGNOR-159381 |
| GSK3A | phosphorylation → up-regulates activity | RELA | SIGNOR-255827 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | MAFA | SIGNOR-159398 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | BCL3 | SIGNOR-276011 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | NCOA3 | SIGNOR-276067 |
| GSK3A | phosphorylation → up-regulates activity | OSBP2 | SIGNOR-264875 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | MAFA | SIGNOR-159390 |
| GSK3A | phosphorylation → up-regulates activity | PPARA | SIGNOR-277431 |
| GSK3A | phosphorylation → up-regulates activity | MAFA | SIGNOR-159365 |
| GSK3A | phosphorylation → unknown | PKD2 | SIGNOR-145306 |
| GSK3A | phosphorylation down-regulates | NOTCH1 | SIGNOR-183969 |
| GSK3A | phosphorylation → down-regulates activity | EIF2B5 | SIGNOR-251215 |
| GSK3A | phosphorylation down-regulates | JUN | SIGNOR-21776 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | MCL1 | SIGNOR-251217 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | IL17RA | SIGNOR-277206 |
| GSK3A | phosphorylation down-regulates | SFPQ | SIGNOR-168385 |
| GSK3A | phosphorylation → up-regulates | MAF | SIGNOR-159358 |
| GSK3A | phosphorylation → up-regulates activity | LRP6 | SIGNOR-275398 |
| GSK3A | phosphorylation → up-regulates activity | MAFA | SIGNOR-159377 |
| GSK3A | phosphorylation → down-regulates activity | ANKRD28 | SIGNOR-264792 |
| GSK3A | phosphorylation down-regulates | GYS1 | SIGNOR-118927 |
| GSK3A | phosphorylation → up-regulates | TSC2 | SIGNOR-149377 |
| GSK3A | phosphorylation down-regulates | MAPT | SIGNOR-60651 |
| GSK3A | phosphorylation down-regulates | MAPT | SIGNOR-29364 |
| GSK3A | phosphorylation down-regulates | MAFB | SIGNOR-159432 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | MYC | SIGNOR-138596 |
| GSK3A | phosphorylation → down-regulates activity | AKT1 | SIGNOR-252434 |
| GSK3A | phosphorylation → up-regulates | MAFB | SIGNOR-159429 |