| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | CDKN1C | Thr310 | GVGSVEQtPRKRLR | phosphorylation down-regulates | 23421998 | SIGNOR-252536 |
| AKT | CDKN1C | Thr310 | GVGSVEQtPRKRLR | phosphorylation down-regulates | 23421998 | SIGNOR-201046 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | CDKN1C PThr310 | phosphorylation down-regulates ⊣ | CDKN1C | 23421998 | SIGNOR-252536 |
| AKT | phosphorylation up-regulates → | CDKN1C PThr310 | phosphorylation down-regulates ⊣ | CDKN1C | 23421998 | SIGNOR-201046 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation![]() down-regulates | CDKN1C | SIGNOR-252536 |
| AKT | phosphorylation![]() down-regulates | CDKN1C | SIGNOR-201046 |