| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK2 | ETV1 | Ser216 | PMYQRQMsEPNIPFP | phosphorylation down-regulates activity | 11551945 | SIGNOR-250146 |
| RPS6KA5 | ETV1 | Ser216 | PMYQRQMsEPNIPFP | phosphorylation up-regulates activity | 12213813 | SIGNOR-262987 |
| RPS6K | ETV1 | Ser216 | PMYQRQMsEPNIPFP | phosphorylation up-regulates activity | 12213813 | SIGNOR-252769 |
| MAPKAPK2 | ETV1 | – | phosphorylation up-regulates | 20626350 | SIGNOR-166625 | |
| MAPKAPK2 | ETV1 | Ser191 | HRFRRQLsEPCNSFP | phosphorylation down-regulates activity | 11551945 | SIGNOR-250145 |
| ATR | ETV1 | – | phosphorylation up-regulates quantity by stabilization | 23284306 | SIGNOR-279355 | |
| PRKACA | ETV1 | Ser191 | HRFRRQLsEPCNSFP | phosphorylation up-regulates activity | 12213813 | SIGNOR-92447 |
| RPS6KA1 | ETV1 | Ser191 | HRFRRQLsEPCNSFP | phosphorylation up-regulates activity | 12213813 | SIGNOR-249162 |
| RPS6K | ETV1 | Ser191 | HRFRRQLsEPCNSFP | phosphorylation up-regulates activity | 12213813 | SIGNOR-252768 |
| PRKACA | ETV1 | Ser334 | PTYQRRGsLQLWQFL | phosphorylation up-regulates | 12213813 | SIGNOR-92455 |
| RPS6KA1 | ETV1 | Ser216 | PMYQRQMsEPNIPFP | phosphorylation up-regulates activity | 12213813 | SIGNOR-249163 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK2 | phosphorylation up-regulates → | ETV1 PSer216 | phosphorylation down-regulates ⊣ | ETV1 | 11551945 | SIGNOR-250146 |
| RPS6KA5 | phosphorylation up-regulates → | ETV1 PSer216 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-262987 |
| RPS6K | phosphorylation up-regulates → | ETV1 PSer216 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-252769 |
| MAPKAPK2 | phosphorylation up-regulates → | ETV1 PSer191 | phosphorylation down-regulates ⊣ | ETV1 | 11551945 | SIGNOR-250145 |
| PRKACA | phosphorylation up-regulates → | ETV1 PSer191 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-92447 |
| RPS6KA1 | phosphorylation up-regulates → | ETV1 PSer191 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-249162 |
| RPS6K | phosphorylation up-regulates → | ETV1 PSer191 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-252768 |
| PRKACA | phosphorylation up-regulates → | ETV1 PSer334 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-92455 |
| RPS6KA1 | phosphorylation up-regulates → | ETV1 PSer216 | phosphorylation up-regulates → | ETV1 | 12213813 | SIGNOR-249163 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPKAPK2 | phosphorylation → down-regulates activity | ETV1 | SIGNOR-250146 |
| RPS6KA5 | phosphorylation → up-regulates activity | ETV1 | SIGNOR-262987 |
| RPS6K | phosphorylation → up-regulates activity | ETV1 | SIGNOR-252769 |
| MAPKAPK2 | phosphorylation → up-regulates | ETV1 | SIGNOR-166625 |
| MAPKAPK2 | phosphorylation → down-regulates activity | ETV1 | SIGNOR-250145 |
| ATR | phosphorylation → up-regulates quantity by stabilization | ETV1 | SIGNOR-279355 |
| PRKACA | phosphorylation → up-regulates activity | ETV1 | SIGNOR-92447 |
| RPS6KA1 | phosphorylation → up-regulates activity | ETV1 | SIGNOR-249162 |
| RPS6K | phosphorylation → up-regulates activity | ETV1 | SIGNOR-252768 |
| PRKACA | phosphorylation → up-regulates | ETV1 | SIGNOR-92455 |
| RPS6KA1 | phosphorylation → up-regulates activity | ETV1 | SIGNOR-249163 |
