| Name | CDK9 |
| ID | P50750 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 19-315 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK9 | SUPT5H | Thr775 | TPMYGSQtPMYGSGS | phosphorylation up-regulates | 16427012 | SIGNOR-143923 |
| CDK9 | POLR2A | Ser1784 | TPTSPNYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203556 |
| CDK9 | MYC | Ser62 | S-->E | phosphorylation down-regulates activity | 31311847 | SIGNOR-279024 |
| CDK9 | POLR2A | Ser1651 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203520 |
| CDK9 | SMAD1 | Ser206 | SSSTYPHsPTSSDPG | phosphorylation down-regulates quantity by destabilization | 19914161 | SIGNOR-161573 |
| CDK9 | POLR2A | Ser1672 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203528 |
| CDK9 | TP53 | Ser33 | LPENNVLsPLPSQAM | phosphorylation unknown | 16552184 | SIGNOR-145315 |
| CDK9 | POLR2A | Ser1861 | TPTSPKYsPTSPKYS | phosphorylation up-regulates | 24385927 | SIGNOR-203560 |
| CDK9 | TP53 | Ser315 | LPNNTSSsPQPKKKP | phosphorylation up-regulates activity | 24173284 | SIGNOR-145311 |
| CDK9 | POLR2A | Ser1924 | SPTSPKYsPTSPTYS | phosphorylation up-regulates | 24385927 | SIGNOR-203596 |
| CDK9 | POLR2A | Ser1644 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203516 |
| CDK9 | RCHY1 | Ser211 | VAQTPMPsEYQNMTV | phosphorylation down-regulates | 23603988 | SIGNOR-201923 |
| CDK9 | POLR2A | Ser1616 | TPQSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203508 |
| CDK9 | UBE2A | Ser120 | LDEPNPNsPANSQAA | phosphorylation up-regulates activity | 22722497 | SIGNOR-279025 |
| CDK9 | SMAD3 | Thr179 | PQSNIPEtPPPGYLS | phosphorylation down-regulates activity | 19914161 | SIGNOR-161589 |
| CDK9 | POLR2A | Ser1896 | SPTSPTYsPTSPVYT | phosphorylation up-regulates | 24385927 | SIGNOR-203584 |
| CDK9 | NCOA2 | Ser499 | MSPGVAGsPRIPPSQ | phosphorylation up-regulates activity | 29170386 | SIGNOR-256099 |
| CDK9 | POLR2A | Ser1763 | TPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203552 |
| CDK9 | SUPT5H | Thr768 | MTSTYGRtPMYGSQT | phosphorylation up-regulates | 16427012 | SIGNOR-143919 |
| CDK9 | POLR2A | Ser1882 | SPTSPTYsPTTPKYS | phosphorylation up-regulates | 24385927 | SIGNOR-203576 |
| CDK9 | POLR2A | Ser1868 | SPTSPKYsPTSPKYS | phosphorylation up-regulates | 24385927 | SIGNOR-203564 |
| CDK9 | POLR2A | Ser1714 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203536 |
| CDK9 | SUPT5H | Thr791 | TPMYGSQtPLQDGSR | phosphorylation up-regulates | 16427012 | SIGNOR-143931 |
| CDK9 | SMAD3 | Ser208 | DAGSPNLsPNPMSPA | phosphorylation down-regulates activity | 19914161 | SIGNOR-161581 |
| CDK9 | SUPT5H | Thr799 | PLQDGSRtPHYGSQT | phosphorylation up-regulates | 16427012 | SIGNOR-143935 |
| CDK9 | SMAD1 | Ser214 | PTSSDPGsPFQMPAD | phosphorylation down-regulates | 19914168 | SIGNOR-161666 |
| CDK9 | AR | Ser83 | QQQQQETsPRQQQQQ | phosphorylation up-regulates activity | 28062857 | SIGNOR-279456 |
| CDK9 | EP300 | – | phosphorylation up-regulates activity | 35745840 | SIGNOR-279690 | |
| CDK9 | H1-4 | Ser187 | KPKKAPKsPAKAKAV | phosphorylation down-regulates activity | 28539972 | SIGNOR-279691 |
| CDK9 | ACTL6A | – | phosphorylation up-regulates activity | 21699904 | SIGNOR-279689 | |
| CDK9 | POLR2A | Ser1917 | SPTSPTYsPTSPKYS | phosphorylation up-regulates | 24385927 | SIGNOR-203592 |
| CDK9 | SMAD1 | Ser195 | PNSSYPNsPGSSSST | phosphorylation down-regulates | 19914168 | SIGNOR-161658 |
| CDK9 | SMAD1 | Ser214 | PTSSDPGsPFQMPAD | phosphorylation down-regulates | 19914161 | SIGNOR-161577 |
| CDK9 | POLR2A | Ser1623 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203512 |
| CDK9 | POLR2A | Ser1693 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203532 |
| CDK9 | POLR2A | Ser1878 | SPKYSPTsPTYSPTT | phosphorylation up-regulates activity | 24385927 | SIGNOR-203572 |
| CDK9 | TP53 | Ser392 | FKTEGPDsD | phosphorylation up-regulates quantity by stabilization | 23603988 | SIGNOR-201931 |
| CDK9 | POLR2A | Ser1931 | SPTSPTYsPTSPKGS | phosphorylation up-regulates | 24385927 | SIGNOR-203600 |
| CDK9 | RCHY1 | Thr217 | PSEYQNMtVDILCND | phosphorylation down-regulates | 23603988 | SIGNOR-201927 |
| CDK9 | SMAD3 | Ser213 | NLSPNPMsPAHNNLD | phosphorylation down-regulates | 19914161 | SIGNOR-161585 |
| CDK9 | SUPT5H | Thr806 | TPHYGSQtPLHDGSR | phosphorylation up-regulates | 16427012 | SIGNOR-143939 |
| CDK9 | POLR2A | Ser1889 | SPTTPKYsPTSPTYS | phosphorylation up-regulates | 24385927 | SIGNOR-203580 |
| CDK9 | SMAD1 | Ser187 | NSHPFPHsPNSSYPN | phosphorylation down-regulates | 19914161 | SIGNOR-161565 |
| CDK9 | NCOA2 | Ser487 | GQPTSMLsPRHRMSP | phosphorylation up-regulates activity | 29170386 | SIGNOR-256097 |
| CDK9 | POLR2A | Ser1735 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203544 |
| CDK9 | POLR2A | Ser1910 | TPTSPKYsPTSPTYS | phosphorylation up-regulates | 24385927 | SIGNOR-203588 |
| CDK9 | POLR2A | Ser1721 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203540 |
| CDK9 | NCOA2 | Ser469 | NYALKMNsPSQSSPG | phosphorylation up-regulates activity | 29170386 | SIGNOR-256096 |
| CDK9 | XRN2 | Thr439 | FTPSGILtPHALGSR | phosphorylation up-regulates activity | 26728557 | SIGNOR-277194 |
| CDK9 | POLR2A | Ser1941 | SPKGSTYsPTSPGYS | phosphorylation up-regulates | 24385927 | SIGNOR-203604 |
| CDK9 | SUPT5H | Thr814 | PLHDGSRtPAQSGAW | phosphorylation up-regulates | 16427012 | SIGNOR-143943 |
| CDK9 | POLR2A | Ser1665 | SPTSPSYsPTSPSYS | phosphorylation up-regulates | 24385927 | SIGNOR-203524 |
| CDK9 | SMAD1 | Ser195 | PNSSYPNsPGSSSST | phosphorylation down-regulates | 19914161 | SIGNOR-161569 |
| CDK9 | NCOA2 | Ser493 | LSPRHRMsSPGVAGS | phosphorylation up-regulates activity | 29170386 | SIGNOR-256098 |
| CDK9 | SMAD3 | Ser213 | NLSPNPMsPAHNNLD | phosphorylation down-regulates | 19914168 | SIGNOR-161678 |
| CDK9 | POLR2A | Ser1948 | SPTSPGYsPTSPTYS | phosphorylation up-regulates | 24385927 | SIGNOR-203608 |
| CDK9 | POLR2A | Ser1875 | SPTSPKYsPTSPTYS | phosphorylation up-regulates | 24385927 | SIGNOR-203568 |
| CDK9 | TP53 | Ser392 | FKTEGPDsD | phosphorylation up-regulates | 23603988 | SIGNOR-201935 |
| CDK9 | SUPT5H | Thr784 | MYGSGSRtPMYGSQT | phosphorylation up-regulates | 16427012 | SIGNOR-143927 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr775 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143923 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1784 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203556 |
| CDK9 | phosphorylation up-regulates → | MYC PSer62 | phosphorylation down-regulates ⊣ | MYC | 31311847 | SIGNOR-279024 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1651 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203520 |
| CDK9 | phosphorylation up-regulates → | SMAD1 PSer206 | phosphorylation down-regulates ⊣ | SMAD1 | 19914161 | SIGNOR-161573 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1672 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203528 |
| CDK9 | phosphorylation up-regulates → | TP53 PSer33 | phosphorylation down-regulates ⊣ | TP53 | 16552184 | SIGNOR-145315 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1861 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203560 |
| CDK9 | phosphorylation up-regulates → | TP53 PSer315 | phosphorylation up-regulates → | TP53 | 24173284 | SIGNOR-145311 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1924 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203596 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1644 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203516 |
| CDK9 | phosphorylation up-regulates → | RCHY1 PSer211 | phosphorylation down-regulates ⊣ | RCHY1 | 23603988 | SIGNOR-201923 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1616 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203508 |
| CDK9 | phosphorylation up-regulates → | UBE2A PSer120 | phosphorylation up-regulates → | UBE2A | 22722497 | SIGNOR-279025 |
| CDK9 | phosphorylation up-regulates → | SMAD3 PThr179 | phosphorylation down-regulates ⊣ | SMAD3 | 19914161 | SIGNOR-161589 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1896 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203584 |
| CDK9 | phosphorylation up-regulates → | NCOA2 PSer499 | phosphorylation up-regulates → | NCOA2 | 29170386 | SIGNOR-256099 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1763 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203552 |
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr768 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143919 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1882 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203576 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1868 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203564 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1714 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203536 |
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr791 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143931 |
| CDK9 | phosphorylation up-regulates → | SMAD3 PSer208 | phosphorylation down-regulates ⊣ | SMAD3 | 19914161 | SIGNOR-161581 |
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr799 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143935 |
| CDK9 | phosphorylation up-regulates → | SMAD1 PSer214 | phosphorylation down-regulates ⊣ | SMAD1 | 19914168 | SIGNOR-161666 |
| CDK9 | phosphorylation up-regulates → | AR PSer83 | phosphorylation up-regulates → | AR | 28062857 | SIGNOR-279456 |
| CDK9 | phosphorylation up-regulates → | H1-4 PSer187 | phosphorylation down-regulates ⊣ | H1-4 | 28539972 | SIGNOR-279691 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1917 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203592 |
| CDK9 | phosphorylation up-regulates → | SMAD1 PSer195 | phosphorylation down-regulates ⊣ | SMAD1 | 19914168 | SIGNOR-161658 |
| CDK9 | phosphorylation up-regulates → | SMAD1 PSer214 | phosphorylation down-regulates ⊣ | SMAD1 | 19914161 | SIGNOR-161577 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1623 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203512 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1693 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203532 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1878 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203572 |
| CDK9 | phosphorylation up-regulates → | TP53 PSer392 | phosphorylation up-regulates → | TP53 | 23603988 | SIGNOR-201931 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1931 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203600 |
| CDK9 | phosphorylation up-regulates → | RCHY1 PThr217 | phosphorylation down-regulates ⊣ | RCHY1 | 23603988 | SIGNOR-201927 |
| CDK9 | phosphorylation up-regulates → | SMAD3 PSer213 | phosphorylation down-regulates ⊣ | SMAD3 | 19914161 | SIGNOR-161585 |
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr806 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143939 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1889 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203580 |
| CDK9 | phosphorylation up-regulates → | SMAD1 PSer187 | phosphorylation down-regulates ⊣ | SMAD1 | 19914161 | SIGNOR-161565 |
| CDK9 | phosphorylation up-regulates → | NCOA2 PSer487 | phosphorylation up-regulates → | NCOA2 | 29170386 | SIGNOR-256097 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1735 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203544 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1910 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203588 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1721 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203540 |
| CDK9 | phosphorylation up-regulates → | NCOA2 PSer469 | phosphorylation up-regulates → | NCOA2 | 29170386 | SIGNOR-256096 |
| CDK9 | phosphorylation up-regulates → | XRN2 PThr439 | phosphorylation up-regulates → | XRN2 | 26728557 | SIGNOR-277194 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1941 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203604 |
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr814 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143943 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1665 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203524 |
| CDK9 | phosphorylation up-regulates → | SMAD1 PSer195 | phosphorylation down-regulates ⊣ | SMAD1 | 19914161 | SIGNOR-161569 |
| CDK9 | phosphorylation up-regulates → | NCOA2 PSer493 | phosphorylation up-regulates → | NCOA2 | 29170386 | SIGNOR-256098 |
| CDK9 | phosphorylation up-regulates → | SMAD3 PSer213 | phosphorylation down-regulates ⊣ | SMAD3 | 19914168 | SIGNOR-161678 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1948 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203608 |
| CDK9 | phosphorylation up-regulates → | POLR2A PSer1875 | phosphorylation up-regulates → | POLR2A | 24385927 | SIGNOR-203568 |
| CDK9 | phosphorylation up-regulates → | TP53 PSer392 | phosphorylation up-regulates → | TP53 | 23603988 | SIGNOR-201935 |
| CDK9 | phosphorylation up-regulates → | SUPT5H PThr784 | phosphorylation up-regulates → | SUPT5H | 16427012 | SIGNOR-143927 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143923 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203556 |
| CDK9 | phosphorylation → down-regulates activity | MYC | SIGNOR-279024 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203520 |
| CDK9 | phosphorylation down-regulates quantity by destabilization | SMAD1 | SIGNOR-161573 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203528 |
| CDK9 | phosphorylation → unknown | TP53 | SIGNOR-145315 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203560 |
| CDK9 | phosphorylation → up-regulates activity | TP53 | SIGNOR-145311 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203596 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203516 |
| CDK9 | phosphorylation down-regulates | RCHY1 | SIGNOR-201923 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203508 |
| CDK9 | phosphorylation → up-regulates activity | UBE2A | SIGNOR-279025 |
| CDK9 | phosphorylation → down-regulates activity | SMAD3 | SIGNOR-161589 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203584 |
| CDK9 | phosphorylation → up-regulates activity | NCOA2 | SIGNOR-256099 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203552 |
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143919 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203576 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203564 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203536 |
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143931 |
| CDK9 | phosphorylation → down-regulates activity | SMAD3 | SIGNOR-161581 |
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143935 |
| CDK9 | phosphorylation down-regulates | SMAD1 | SIGNOR-161666 |
| CDK9 | phosphorylation → up-regulates activity | AR | SIGNOR-279456 |
| CDK9 | phosphorylation → up-regulates activity | EP300 | SIGNOR-279690 |
| CDK9 | phosphorylation → down-regulates activity | H1-4 | SIGNOR-279691 |
| CDK9 | phosphorylation → up-regulates activity | ACTL6A | SIGNOR-279689 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203592 |
| CDK9 | phosphorylation down-regulates | SMAD1 | SIGNOR-161658 |
| CDK9 | phosphorylation down-regulates | SMAD1 | SIGNOR-161577 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203512 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203532 |
| CDK9 | phosphorylation → up-regulates activity | POLR2A | SIGNOR-203572 |
| CDK9 | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-201931 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203600 |
| CDK9 | phosphorylation down-regulates | RCHY1 | SIGNOR-201927 |
| CDK9 | phosphorylation down-regulates | SMAD3 | SIGNOR-161585 |
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143939 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203580 |
| CDK9 | phosphorylation down-regulates | SMAD1 | SIGNOR-161565 |
| CDK9 | phosphorylation → up-regulates activity | NCOA2 | SIGNOR-256097 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203544 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203588 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203540 |
| CDK9 | phosphorylation → up-regulates activity | NCOA2 | SIGNOR-256096 |
| CDK9 | phosphorylation → up-regulates activity | XRN2 | SIGNOR-277194 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203604 |
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143943 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203524 |
| CDK9 | phosphorylation down-regulates | SMAD1 | SIGNOR-161569 |
| CDK9 | phosphorylation → up-regulates activity | NCOA2 | SIGNOR-256098 |
| CDK9 | phosphorylation down-regulates | SMAD3 | SIGNOR-161678 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203608 |
| CDK9 | phosphorylation → up-regulates | POLR2A | SIGNOR-203568 |
| CDK9 | phosphorylation → up-regulates | TP53 | SIGNOR-201935 |
| CDK9 | phosphorylation → up-regulates | SUPT5H | SIGNOR-143927 |