| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PP1 | CDK9 | Ser175 | FGLARAFsLAKNSQP | dephosphorylation up-regulates | 21533037 | SIGNOR-264671 |
| PPP1CC | CDK9 | Ser175 | FGLARAFsLAKNSQP | dephosphorylation up-regulates | 21533037 | SIGNOR-173450 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PP1 | dephosphorylation down-regulates ⊣ | CDK9 PSer175 | dephosphorylation down-regulates ⊣ | CDK9 | 21533037 | SIGNOR-264671 |
| PPP1CC | dephosphorylation down-regulates ⊣ | CDK9 PSer175 | dephosphorylation down-regulates ⊣ | CDK9 | 21533037 | SIGNOR-173450 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PP1 | dephosphorylation → up-regulates | CDK9 | SIGNOR-264671 |
| PPP1CC | dephosphorylation → up-regulates | CDK9 | SIGNOR-173450 |