Entity Details

Name	PAPOLA
ID	P51003
Role	substrate
Enzymatic Domains
View in

Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ERK1/2	PAPOLA	Ser537 View in OncoXplorer	DNSMSVPsPTSATKT	phosphorylation up-regulates activity	34048556	SIGNOR-268341
ERK1/2	PAPOLA	Ser558	GSSQGRNsPAPAVTA	phosphorylation up-regulates activity	34048556	SIGNOR-268343
CDK1	PAPOLA	Ser537 View in OncoXplorer	DNSMSVPsPTSATKT	phosphorylation up-regulates activity	34048556	SIGNOR-268338
CDK1	PAPOLA	Ser545 View in OncoXplorer	PTSATKTsPLNSSGS	phosphorylation up-regulates activity	34048556	SIGNOR-268339
CDK1	PAPOLA	Ser558	GSSQGRNsPAPAVTA	phosphorylation up-regulates activity	34048556	SIGNOR-268340
ERK1/2	PAPOLA	Ser545 View in OncoXplorer	PTSATKTsPLNSSGS	phosphorylation up-regulates activity	34048556	SIGNOR-268342

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
ERK1/2	phosphorylation up-regulates →	PAPOLA PSer537	phosphorylation up-regulates →	PAPOLA	34048556	SIGNOR-268341
ERK1/2	phosphorylation up-regulates →	PAPOLA PSer558	phosphorylation up-regulates →	PAPOLA	34048556	SIGNOR-268343
CDK1	phosphorylation up-regulates →	PAPOLA PSer537	phosphorylation up-regulates →	PAPOLA	34048556	SIGNOR-268338
CDK1	phosphorylation up-regulates →	PAPOLA PSer545	phosphorylation up-regulates →	PAPOLA	34048556	SIGNOR-268339
CDK1	phosphorylation up-regulates →	PAPOLA PSer558	phosphorylation up-regulates →	PAPOLA	34048556	SIGNOR-268340
ERK1/2	phosphorylation up-regulates →	PAPOLA PSer545	phosphorylation up-regulates →	PAPOLA	34048556	SIGNOR-268342

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ERK1/2	phosphorylation → up-regulates activity	PAPOLA	SIGNOR-268341
ERK1/2	phosphorylation → up-regulates activity	PAPOLA	SIGNOR-268343
CDK1	phosphorylation → up-regulates activity	PAPOLA	SIGNOR-268338
CDK1	phosphorylation → up-regulates activity	PAPOLA	SIGNOR-268339
CDK1	phosphorylation → up-regulates activity	PAPOLA	SIGNOR-268340
ERK1/2	phosphorylation → up-regulates activity	PAPOLA	SIGNOR-268342