| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTEN | RAB7A | Tyr183 | QETEVELyNEFPEPI | dephosphorylation up-regulates activity | 26869029 | SIGNOR-276959 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTEN | dephosphorylation down-regulates ⊣ | RAB7A PTyr183 | dephosphorylation down-regulates ⊣ | RAB7A | 26869029 | SIGNOR-276959 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTEN | dephosphorylation → up-regulates activity | RAB7A | SIGNOR-276959 |