Entity Details

Name SCNN1B
ID P51168
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ERK1/2SCNN1B–phosphorylation
down-regulates quantity by destabilization		11805112SIGNOR-270163
MAPK1SCNN1BThr615
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QALPIPGtPPPNYDSphosphorylation
down-regulates quantity by destabilization		11805112SIGNOR-249446
MAPK3SCNN1BThr615
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QALPIPGtPPPNYDSphosphorylation
down-regulates quantity by destabilization		11805112SIGNOR-249447
GbetaSCNN1B–phosphorylation
down-regulates quantity by destabilization		11805112SIGNOR-270050
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
SCNN1B
PThr615		phosphorylation
down-regulates
⊣		SCNN1B11805112SIGNOR-249446
MAPK3phosphorylation
up-regulates
→
SCNN1B
PThr615		phosphorylation
down-regulates
⊣		SCNN1B11805112SIGNOR-249447
Regulator Mechanism/Effect Target SIGNOR-ID
ERK1/2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SCNN1BSIGNOR-270163
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SCNN1BSIGNOR-249446
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SCNN1BSIGNOR-249447
Gbetaphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SCNN1BSIGNOR-270050