| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | SCNN1G | Thr622 | LGTQVPGtPPPKYNT | phosphorylation down-regulates quantity by destabilization | 11805112 | SIGNOR-249449 |
| MAPK1 | SCNN1G | Thr622 | LGTQVPGtPPPKYNT | phosphorylation down-regulates quantity by destabilization | 11805112 | SIGNOR-249448 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | SCNN1G PThr622 | phosphorylation down-regulates ⊣ | SCNN1G | 11805112 | SIGNOR-249449 |
| MAPK1 | phosphorylation up-regulates → | SCNN1G PThr622 | phosphorylation down-regulates ⊣ | SCNN1G | 11805112 | SIGNOR-249448 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation![]() down-regulates quantity by destabilization | SCNN1G | SIGNOR-249449 |
| MAPK1 | phosphorylation![]() down-regulates quantity by destabilization | SCNN1G | SIGNOR-249448 |