| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK3 | CCR5 | Ser342 | ASSVYTRsTGEQEIS | phosphorylation down-regulates activity | 10085131 | SIGNOR-249675 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK3 | phosphorylation up-regulates → | CCR5 PSer342 | phosphorylation down-regulates ⊣ | CCR5 | 10085131 | SIGNOR-249675 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GRK3 | phosphorylation → down-regulates activity | CCR5 | SIGNOR-249675 |