| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1D | RPS6KA3 | Ser386 | HQLFRGFsFVAITSD | dephosphorylation down-regulates activity | 15206906 | SIGNOR-248322 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1D | dephosphorylation down-regulates ⊣ | RPS6KA3 PSer386 | dephosphorylation up-regulates → | RPS6KA3 | 15206906 | SIGNOR-248322 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPM1D | dephosphorylation → down-regulates activity | RPS6KA3 | SIGNOR-248322 |
