Entity Details

Name ITK_Tyr216
ID P51813
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
BTKBMXTyr216SSTSLAQyDSNSKKIphosphorylation
up-regulates		12573241SIGNOR-98028
ITKBMXTyr216SSTSLAQyDSNSKKIphosphorylation
up-regulates activity		12573241SIGNOR-251331
TECBMXTyr216SSTSLAQyDSNSKKIphosphorylation
up-regulates activity		12573241SIGNOR-246647
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
BTKphosphorylation
up-regulates
→
BMX
PTyr216		phosphorylation
up-regulates
→		BMX12573241SIGNOR-98028
ITKphosphorylation
up-regulates
→
BMX
PTyr216		phosphorylation
up-regulates
→		BMX12573241SIGNOR-251331
TECphosphorylation
up-regulates
→
BMX
PTyr216		phosphorylation
up-regulates
→		BMX12573241SIGNOR-246647
Regulator Mechanism/Effect Target SIGNOR-ID
BTKphosphorylation
→
up-regulates 		BMXSIGNOR-98028
ITKphosphorylation
→
up-regulates activity 		BMXSIGNOR-251331
TECphosphorylation
→
up-regulates activity 		BMXSIGNOR-246647