| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | ARHGDIA | Ser174 | KGMLARGsYSIKSRF | phosphorylation down-regulates | 15225553 | SIGNOR-126654 |
| PRKACA | ARHGDIA | Ser174 | KGMLARGsYSIKSRF | phosphorylation down-regulates | 18768928 | SIGNOR-180576 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | phosphorylation up-regulates → | ARHGDIA PSer174 | phosphorylation down-regulates ⊣ | ARHGDIA | 15225553 | SIGNOR-126654 |
| PRKACA | phosphorylation up-regulates → | ARHGDIA PSer174 | phosphorylation down-regulates ⊣ | ARHGDIA | 18768928 | SIGNOR-180576 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK1 | phosphorylation down-regulates | ARHGDIA | SIGNOR-126654 |
| PRKACA | phosphorylation down-regulates | ARHGDIA | SIGNOR-180576 |
