| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | ARHGDIB | Ser31 | YKPPPQKsLKELQEM | phosphorylation down-regulates | 22469974 | SIGNOR-196765 |
| SRC | ARHGDIB | Tyr153 | YGPRPEEyEFLTPVE | phosphorylation unknown | 19321744 | SIGNOR-184908 |
| SRC | ARHGDIB | Tyr24 | ELDSKLNyKPPPQKS | phosphorylation unknown | 19321744 | SIGNOR-184912 |
| MAP3K20 | ARHGDIB | – | phosphorylation down-regulates activity | 19272173 | SIGNOR-279633 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | ARHGDIB PSer31 | phosphorylation down-regulates ⊣ | ARHGDIB | 22469974 | SIGNOR-196765 |
| SRC | phosphorylation up-regulates → | ARHGDIB PTyr153 | phosphorylation down-regulates ⊣ | ARHGDIB | 19321744 | SIGNOR-184908 |
| SRC | phosphorylation up-regulates → | ARHGDIB PTyr24 | phosphorylation down-regulates ⊣ | ARHGDIB | 19321744 | SIGNOR-184912 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation down-regulates | ARHGDIB | SIGNOR-196765 |
| SRC | phosphorylation → unknown | ARHGDIB | SIGNOR-184908 |
| SRC | phosphorylation → unknown | ARHGDIB | SIGNOR-184912 |
| MAP3K20 | phosphorylation → down-regulates activity | ARHGDIB | SIGNOR-279633 |
