| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | STAT2 | Ser381 | RKFNILTsNQKTLTP | phosphorylation down-regulates quantity by destabilization | 31843895 | SIGNOR-276760 |
| GSK3B | STAT2 | Ser381 | RKFNILTsNQKTLTP | phosphorylation down-regulates quantity by destabilization | 31843895 | SIGNOR-276763 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | phosphorylation up-regulates → | STAT2 PSer381 | phosphorylation down-regulates ⊣ | STAT2 | 31843895 | SIGNOR-276760 |
| GSK3B | phosphorylation up-regulates → | STAT2 PSer381 | phosphorylation down-regulates ⊣ | STAT2 | 31843895 | SIGNOR-276763 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3A | phosphorylation![]() down-regulates quantity by destabilization | STAT2 | SIGNOR-276760 |
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | STAT2 | SIGNOR-276763 |