Entity Details

Name STAT2_Tyr690
ID P52630
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
JAK1STAT2Tyr690NLQERRKyLKHRLIVphosphorylation
up-regulates activity		9020188SIGNOR-251344
PTPRGSTAT2Tyr690NLQERRKyLKHRLIVdephosphorylation
up-regulates activity		25624455SIGNOR-254728
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
JAK1phosphorylation
up-regulates
→
STAT2
PTyr690		phosphorylation
up-regulates
→		STAT29020188SIGNOR-251344
PTPRGdephosphorylation
down-regulates
⊣
STAT2
PTyr690		dephosphorylation
down-regulates
⊣		STAT225624455SIGNOR-254728
Regulator Mechanism/Effect Target SIGNOR-ID
JAK1phosphorylation
→
up-regulates activity 		STAT2SIGNOR-251344
PTPRGdephosphorylation
→
up-regulates activity 		STAT2SIGNOR-254728