| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | CHN2 | Tyr21 | VSSDAEEyQPPIWKS | phosphorylation down-regulates | 17560670 | SIGNOR-155713 |
| FYN | CHN2 | Tyr21 | VSSDAEEyQPPIWKS | phosphorylation down-regulates | 17560670 | SIGNOR-155709 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | CHN2 PTyr21 | phosphorylation down-regulates ⊣ | CHN2 | 17560670 | SIGNOR-155713 |
| FYN | phosphorylation up-regulates → | CHN2 PTyr21 | phosphorylation down-regulates ⊣ | CHN2 | 17560670 | SIGNOR-155709 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation![]() down-regulates | CHN2 | SIGNOR-155713 |
| FYN | phosphorylation![]() down-regulates | CHN2 | SIGNOR-155709 |