| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | PDX1 | Ser268 | LPPGLSAsPQPSSVA | phosphorylation down-regulates quantity | 19833727 | SIGNOR-255566 |
| HIPK2 | PDX1 | Ser268 | LPPGLSAsPQPSSVA | phosphorylation unknown | 20637728 | SIGNOR-255539 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | PDX1 PSer268 | phosphorylation down-regulates ⊣ | PDX1 | 19833727 | SIGNOR-255566 |
| HIPK2 | phosphorylation up-regulates → | PDX1 PSer268 | phosphorylation down-regulates ⊣ | PDX1 | 20637728 | SIGNOR-255539 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → down-regulates quantity | PDX1 | SIGNOR-255566 |
| HIPK2 | phosphorylation → unknown | PDX1 | SIGNOR-255539 |