Entity Details

Name NUP98
ID P52948
Role substrate
Enzymatic Domains
Peptidase S59 738-880
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1NUP98Thr670 IAKPIPQtPESAGNKphosphorylation
down-regulates activity
21335236SIGNOR-172225
CDK1NUP98Ser623 RDSENLAsPSEYPENphosphorylation
down-regulates activity
21335236SIGNOR-172221
NEK6NUP98Ser608 VLKNLNNsNLFSPVNphosphorylation
down-regulates activity
21335236SIGNOR-273892
CDK1NUP98Ser612 LNNSNLFsPVNRDSEphosphorylation
down-regulates activity
21335236SIGNOR-172217
NEK6NUP98Ser839 TSRCLIKsPDRLADIphosphorylation
down-regulates activity
21335236SIGNOR-273893
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
NUP98
PThr670
phosphorylation
down-regulates
NUP9821335236SIGNOR-172225
CDK1phosphorylation
up-regulates
NUP98
PSer623
phosphorylation
down-regulates
NUP9821335236SIGNOR-172221
NEK6phosphorylation
up-regulates
NUP98
PSer608
phosphorylation
down-regulates
NUP9821335236SIGNOR-273892
CDK1phosphorylation
up-regulates
NUP98
PSer612
phosphorylation
down-regulates
NUP9821335236SIGNOR-172217
NEK6phosphorylation
up-regulates
NUP98
PSer839
phosphorylation
down-regulates
NUP9821335236SIGNOR-273893
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation

down-regulates activity
NUP98SIGNOR-172225
CDK1phosphorylation

down-regulates activity
NUP98SIGNOR-172221
NEK6phosphorylation

down-regulates activity
NUP98SIGNOR-273892
CDK1phosphorylation

down-regulates activity
NUP98SIGNOR-172217
NEK6phosphorylation

down-regulates activity
NUP98SIGNOR-273893