| Name | NUP98 |
| ID | P52948 |
| Role | substrate |
| Enzymatic Domains |
Peptidase S59 738-880 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | NUP98 | Thr670 | IAKPIPQtPESAGNK | phosphorylation down-regulates activity | 21335236 | SIGNOR-172225 |
| CDK1 | NUP98 | Ser623 | RDSENLAsPSEYPEN | phosphorylation down-regulates activity | 21335236 | SIGNOR-172221 |
| NEK6 | NUP98 | Ser608 | VLKNLNNsNLFSPVN | phosphorylation down-regulates activity | 21335236 | SIGNOR-273892 |
| CDK1 | NUP98 | Ser612 | LNNSNLFsPVNRDSE | phosphorylation down-regulates activity | 21335236 | SIGNOR-172217 |
| NEK6 | NUP98 | Ser839 | TSRCLIKsPDRLADI | phosphorylation down-regulates activity | 21335236 | SIGNOR-273893 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | NUP98 PThr670 | phosphorylation down-regulates ⊣ | NUP98 | 21335236 | SIGNOR-172225 |
| CDK1 | phosphorylation up-regulates → | NUP98 PSer623 | phosphorylation down-regulates ⊣ | NUP98 | 21335236 | SIGNOR-172221 |
| NEK6 | phosphorylation up-regulates → | NUP98 PSer608 | phosphorylation down-regulates ⊣ | NUP98 | 21335236 | SIGNOR-273892 |
| CDK1 | phosphorylation up-regulates → | NUP98 PSer612 | phosphorylation down-regulates ⊣ | NUP98 | 21335236 | SIGNOR-172217 |
| NEK6 | phosphorylation up-regulates → | NUP98 PSer839 | phosphorylation down-regulates ⊣ | NUP98 | 21335236 | SIGNOR-273893 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation → down-regulates activity | NUP98 | SIGNOR-172225 |
| CDK1 | phosphorylation → down-regulates activity | NUP98 | SIGNOR-172221 |
| NEK6 | phosphorylation → down-regulates activity | NUP98 | SIGNOR-273892 |
| CDK1 | phosphorylation → down-regulates activity | NUP98 | SIGNOR-172217 |
| NEK6 | phosphorylation → down-regulates activity | NUP98 | SIGNOR-273893 |