| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| INSR | BLVRA | Tyr228 | PGLKRNRyLSFHFKS | phosphorylation up-regulates activity | 15870194 | SIGNOR-275515 |
| INSR | BLVRA | Tyr291 | LAEEIQKyCCSRK | phosphorylation up-regulates activity | 15870194 | SIGNOR-275516 |
| INSR | BLVRA | Tyr198 | EERKEDQyMKMTVCL | phosphorylation up-regulates activity | 15870194 | SIGNOR-275514 |
| PRKCD | BLVRA | Ser237 | SFHFKSGsLENVPNV | phosphorylation up-regulates activity | 22584576 | SIGNOR-275526 |
| AKT1 | BLVRA | Ser230 | LKRNRYLsFHFKSGS | phosphorylation up-regulates activity | 15870194 | SIGNOR-275517 |
| PRKCD | BLVRA | Ser33 | DLRNPHPsSAFLNLI | phosphorylation up-regulates activity | 22584576 | SIGNOR-275527 |
| PRKCD | BLVRA | Ser21 | VGVGRAGsVRMRDLR | phosphorylation up-regulates activity | 22584576 | SIGNOR-275525 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| INSR | phosphorylation up-regulates → | BLVRA PTyr228 | phosphorylation up-regulates → | BLVRA | 15870194 | SIGNOR-275515 |
| INSR | phosphorylation up-regulates → | BLVRA PTyr291 | phosphorylation up-regulates → | BLVRA | 15870194 | SIGNOR-275516 |
| INSR | phosphorylation up-regulates → | BLVRA PTyr198 | phosphorylation up-regulates → | BLVRA | 15870194 | SIGNOR-275514 |
| PRKCD | phosphorylation up-regulates → | BLVRA PSer237 | phosphorylation up-regulates → | BLVRA | 22584576 | SIGNOR-275526 |
| AKT1 | phosphorylation up-regulates → | BLVRA PSer230 | phosphorylation up-regulates → | BLVRA | 15870194 | SIGNOR-275517 |
| PRKCD | phosphorylation up-regulates → | BLVRA PSer33 | phosphorylation up-regulates → | BLVRA | 22584576 | SIGNOR-275527 |
| PRKCD | phosphorylation up-regulates → | BLVRA PSer21 | phosphorylation up-regulates → | BLVRA | 22584576 | SIGNOR-275525 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| INSR | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275515 |
| INSR | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275516 |
| INSR | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275514 |
| PRKCD | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275526 |
| AKT1 | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275517 |
| PRKCD | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275527 |
| PRKCD | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275525 |
