Entity Details

Name CHEK2_Thr182
ID P54132
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHEK2BLMThr182SHFVRVStAQKSKKGphosphorylation
down-regulates quantity by destabilization		26028025SIGNOR-276908
CHEK1BLMThr182SHFVRVStAQKSKKGphosphorylation
down-regulates quantity by destabilization		26028025SIGNOR-276909
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CHEK2phosphorylation
up-regulates
→
BLM
PThr182		phosphorylation
down-regulates
⊣		BLM26028025SIGNOR-276908
CHEK1phosphorylation
up-regulates
→
BLM
PThr182		phosphorylation
down-regulates
⊣		BLM26028025SIGNOR-276909
Regulator Mechanism/Effect Target SIGNOR-ID
CHEK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		BLMSIGNOR-276908
CHEK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		BLMSIGNOR-276909