| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | BLM | Ser175 | SFVTPPQsHFVRVST | phosphorylation down-regulates quantity by destabilization | 26028025 | SIGNOR-276911 |
| CyclinA2/CDK2 | BLM | Ser175 | SFVTPPQsHFVRVST | phosphorylation down-regulates quantity by destabilization | 26028025 | SIGNOR-276910 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | BLM PSer175 | phosphorylation down-regulates ⊣ | BLM | 26028025 | SIGNOR-276911 |
| CyclinA2/CDK2 | phosphorylation up-regulates → | BLM PSer175 | phosphorylation down-regulates ⊣ | BLM | 26028025 | SIGNOR-276910 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | BLM | SIGNOR-276911 |
| CyclinA2/CDK2 | phosphorylation![]() down-regulates quantity by destabilization | BLM | SIGNOR-276910 |