Entity Details

Name GSK3B_Ser175
ID P54132
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinA2/CDK2BLMSer175SFVTPPQsHFVRVSTphosphorylation
down-regulates quantity by destabilization		26028025SIGNOR-276910
GSK3BBLMSer175SFVTPPQsHFVRVSTphosphorylation
down-regulates quantity by destabilization		26028025SIGNOR-276911
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinA2/CDK2phosphorylation
up-regulates
→
BLM
PSer175		phosphorylation
down-regulates
⊣		BLM26028025SIGNOR-276910
GSK3Bphosphorylation
up-regulates
→
BLM
PSer175		phosphorylation
down-regulates
⊣		BLM26028025SIGNOR-276911
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinA2/CDK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		BLMSIGNOR-276910
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		BLMSIGNOR-276911