| Name | EPHB3 |
| ID | P54753 |
| Role | kinase |
| Enzymatic Domains |
Eph LBD 39-217 PROSITE-ProRule
Fibronectin type-III 1 339-451 PROSITE-ProRule
Fibronectin type-III 2 452-545 PROSITE-ProRule
Protein kinase 633-896 PROSITE-ProRule
SAM 925-989 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EPHB3 | CDKN1B | Thr187 | NAGSVEQtPKKPGLR | phosphorylation down-regulates activity | 10389236 | SIGNOR-279406 |
| EPHB3 | EPHB3 | Tyr614 | VYIDPFTyEDPNEAV | phosphorylation up-regulates activity | 9674711 | SIGNOR-251126 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EPHB3 | phosphorylation up-regulates → | CDKN1B PThr187 | phosphorylation down-regulates ⊣ | CDKN1B | 10389236 | SIGNOR-279406 |
| EPHB3 | phosphorylation up-regulates → | EPHB3 PTyr614 | phosphorylation up-regulates → | EPHB3 | 9674711 | SIGNOR-251126 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EPHB3 | phosphorylation → down-regulates activity | CDKN1B | SIGNOR-279406 |
| EPHB3 | phosphorylation → up-regulates activity | EPHB3 | SIGNOR-251126 |