| Name | EIF5 |
| ID | P55010 |
| Role | substrate |
| Enzymatic Domains |
W2 233-392 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2B | EIF5 | Ser389 | LKEAEEEsSGGEEED | phosphorylation up-regulates activity | 11861906 | SIGNOR-251069 |
| CSNK2B | EIF5 | Ser174 | DKENGSVsSSETPPP | phosphorylation up-regulates activity | 11861906 | SIGNOR-251068 |
| CSNK2A1 | EIF5 | Ser390 | KEAEEESsGGEEEDE | phosphorylation up-regulates | 18649047 | SIGNOR-179546 |
| CSNK2A1 | EIF5 | Ser174 | DKENGSVsSSETPPP | phosphorylation up-regulates activity | 11861906 | SIGNOR-250861 |
| CSNK2A1 | EIF5 | Ser389 | LKEAEEEsSGGEEED | phosphorylation up-regulates | 18649047 | SIGNOR-179542 |
| CSNK2A1 | EIF5 | Ser390 | KEAEEESsGGEEEDE | phosphorylation up-regulates | 16227438 | SIGNOR-141159 |
| CSNK2B | EIF5 | Ser390 | KEAEEESsGGEEEDE | phosphorylation up-regulates activity | 11861906 | SIGNOR-251070 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2B | phosphorylation up-regulates → | EIF5 PSer389 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-251069 |
| CSNK2B | phosphorylation up-regulates → | EIF5 PSer174 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-251068 |
| CSNK2A1 | phosphorylation up-regulates → | EIF5 PSer390 | phosphorylation up-regulates → | EIF5 | 18649047 | SIGNOR-179546 |
| CSNK2A1 | phosphorylation up-regulates → | EIF5 PSer174 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-250861 |
| CSNK2A1 | phosphorylation up-regulates → | EIF5 PSer389 | phosphorylation up-regulates → | EIF5 | 18649047 | SIGNOR-179542 |
| CSNK2A1 | phosphorylation up-regulates → | EIF5 PSer390 | phosphorylation up-regulates → | EIF5 | 16227438 | SIGNOR-141159 |
| CSNK2B | phosphorylation up-regulates → | EIF5 PSer390 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-251070 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2B | phosphorylation → up-regulates activity | EIF5 | SIGNOR-251069 |
| CSNK2B | phosphorylation → up-regulates activity | EIF5 | SIGNOR-251068 |
| CSNK2A1 | phosphorylation → up-regulates | EIF5 | SIGNOR-179546 |
| CSNK2A1 | phosphorylation → up-regulates activity | EIF5 | SIGNOR-250861 |
| CSNK2A1 | phosphorylation → up-regulates | EIF5 | SIGNOR-179542 |
| CSNK2A1 | phosphorylation → up-regulates | EIF5 | SIGNOR-141159 |
| CSNK2B | phosphorylation → up-regulates activity | EIF5 | SIGNOR-251070 |