Entity Details

Name ADAR
ID P55265
Role substrate
Enzymatic Domains
Z-binding 1 133-199
PROSITE-ProRule|PubMed|PubMed|PubMed
Z-binding 2 293-357
PROSITE-ProRule
DRBM 1 503-571
PROSITE-ProRule
DRBM 2 614-682
PROSITE-ProRule
DRBM 3 726-794
PROSITE-ProRule|PubMed
A to I editase 886-1221
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTADARThr1033RLGERLRtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-266357
AKT3ADARThr1033RLGERLRtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-276191
AKT1ADARThr1033RLGERLRtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-276193
AKT2ADARThr1033RLGERLRtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-276192
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
ADAR
PThr1033		phosphorylation
down-regulates
⊣		ADAR31095429SIGNOR-266357
AKT3phosphorylation
up-regulates
→
ADAR
PThr1033		phosphorylation
down-regulates
⊣		ADAR31095429SIGNOR-276191
AKT1phosphorylation
up-regulates
→
ADAR
PThr1033		phosphorylation
down-regulates
⊣		ADAR31095429SIGNOR-276193
AKT2phosphorylation
up-regulates
→
ADAR
PThr1033		phosphorylation
down-regulates
⊣		ADAR31095429SIGNOR-276192
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
down-regulates activity 		ADARSIGNOR-266357
AKT3phosphorylation
→
down-regulates activity 		ADARSIGNOR-276191
AKT1phosphorylation
→
down-regulates activity 		ADARSIGNOR-276193
AKT2phosphorylation
→
down-regulates activity 		ADARSIGNOR-276192