| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1E | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 11583622 | SIGNOR-250806 |
| MAPK8 | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 25077544 | SIGNOR-279076 |
| MAPK9 | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 25077544 | SIGNOR-279220 |
| CSNK1A1 | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 11583622 | SIGNOR-250786 |
| CSNK2A1 | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 11583622 | SIGNOR-250831 |
| CSNK2B | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 11583622 | SIGNOR-251054 |
| CSNK2A2 | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 11583622 | SIGNOR-250979 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1E | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-250806 |
| MAPK8 | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 25077544 | SIGNOR-279076 |
| MAPK9 | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 25077544 | SIGNOR-279220 |
| CSNK1A1 | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-250786 |
| CSNK2A1 | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-250831 |
| CSNK2B | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-251054 |
| CSNK2A2 | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-250979 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK1E | phosphorylation → up-regulates activity | BID | SIGNOR-250806 |
| MAPK8 | phosphorylation → up-regulates activity | BID | SIGNOR-279076 |
| MAPK9 | phosphorylation → up-regulates activity | BID | SIGNOR-279220 |
| CSNK1A1 | phosphorylation → up-regulates activity | BID | SIGNOR-250786 |
| CSNK2A1 | phosphorylation → up-regulates activity | BID | SIGNOR-250831 |
| CSNK2B | phosphorylation → up-regulates activity | BID | SIGNOR-251054 |
| CSNK2A2 | phosphorylation → up-regulates activity | BID | SIGNOR-250979 |
