| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | EIF6 | Ser235 | QPSTIATsMRDSLID | phosphorylation down-regulates activity | 14654845 | SIGNOR-249245 |
| PRKCA | EIF6 | Ser235 | QPSTIATsMRDSLID | phosphorylation unknown | 14654845 | SIGNOR-119600 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | EIF6 PSer235 | phosphorylation down-regulates ⊣ | EIF6 | 14654845 | SIGNOR-249245 |
| PRKCA | phosphorylation up-regulates → | EIF6 PSer235 | phosphorylation down-regulates ⊣ | EIF6 | 14654845 | SIGNOR-119600 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation → down-regulates activity | EIF6 | SIGNOR-249245 |
| PRKCA | phosphorylation → unknown | EIF6 | SIGNOR-119600 |
