| Name | PER3 |
| ID | P56645 |
| Role | substrate |
| Enzymatic Domains |
PAS 1 121-188 PROSITE-ProRule
PAS 2 262-328 PROSITE-ProRule
PAC 337-380 |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1E | PER3 | Ser622 | ILSTAMLsLGSGISQ | phosphorylation down-regulates activity | 11865049 | SIGNOR-250815 |
| CSNK1E | PER3 | – | phosphorylation down-regulates quantity by destabilization | 11865049 | SIGNOR-267996 | |
| CSNK1E | PER3 | Ser628 | LSLGSGIsQCGYSST | phosphorylation down-regulates activity | 11865049 | SIGNOR-250817 |
| CSNK1E | PER3 | Ser625 | TAMLSLGsGISQCGY | phosphorylation down-regulates activity | 11865049 | SIGNOR-250816 |
| CSNK1D | PER3 | – | phosphorylation down-regulates quantity by destabilization | 11865049 | SIGNOR-267998 | |
| CSNK1E | PER3 | Ser634 | ISQCGYSsTIVHVPP | phosphorylation down-regulates activity | 11865049 | SIGNOR-250819 |
| CSNK1E | PER3 | Thr635 | SQCGYSStIVHVPPP | phosphorylation down-regulates activity | 11865049 | SIGNOR-250820 |
| CSNK1E | PER3 | Ser633 | GISQCGYsSTIVHVP | phosphorylation down-regulates activity | 11865049 | SIGNOR-250818 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1E | phosphorylation up-regulates → | PER3 PSer622 | phosphorylation down-regulates ⊣ | PER3 | 11865049 | SIGNOR-250815 |
| CSNK1E | phosphorylation up-regulates → | PER3 PSer628 | phosphorylation down-regulates ⊣ | PER3 | 11865049 | SIGNOR-250817 |
| CSNK1E | phosphorylation up-regulates → | PER3 PSer625 | phosphorylation down-regulates ⊣ | PER3 | 11865049 | SIGNOR-250816 |
| CSNK1E | phosphorylation up-regulates → | PER3 PSer634 | phosphorylation down-regulates ⊣ | PER3 | 11865049 | SIGNOR-250819 |
| CSNK1E | phosphorylation up-regulates → | PER3 PThr635 | phosphorylation down-regulates ⊣ | PER3 | 11865049 | SIGNOR-250820 |
| CSNK1E | phosphorylation up-regulates → | PER3 PSer633 | phosphorylation down-regulates ⊣ | PER3 | 11865049 | SIGNOR-250818 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK1E | phosphorylation → down-regulates activity | PER3 | SIGNOR-250815 |
| CSNK1E | phosphorylation down-regulates quantity by destabilization | PER3 | SIGNOR-267996 |
| CSNK1E | phosphorylation → down-regulates activity | PER3 | SIGNOR-250817 |
| CSNK1E | phosphorylation → down-regulates activity | PER3 | SIGNOR-250816 |
| CSNK1D | phosphorylation down-regulates quantity by destabilization | PER3 | SIGNOR-267998 |
| CSNK1E | phosphorylation → down-regulates activity | PER3 | SIGNOR-250819 |
| CSNK1E | phosphorylation → down-regulates activity | PER3 | SIGNOR-250820 |
| CSNK1E | phosphorylation → down-regulates activity | PER3 | SIGNOR-250818 |