Entity Details

Name SOX10
ID P56693
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BSOX10–phosphorylation
down-regulates quantity		26461473SIGNOR-279617
ERK1/2SOX10Thr240GQSHGPPtPPTTPKTphosphorylation
down-regulates activity		29295999SIGNOR-277821
ERK1/2SOX10Thr244GPPTPPTtPKTELQSphosphorylation
down-regulates activity		29295999SIGNOR-277820
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ERK1/2phosphorylation
up-regulates
→
SOX10
PThr240		phosphorylation
down-regulates
⊣		SOX1029295999SIGNOR-277821
ERK1/2phosphorylation
up-regulates
→
SOX10
PThr244		phosphorylation
down-regulates
⊣		SOX1029295999SIGNOR-277820
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
→
down-regulates quantity 		SOX10SIGNOR-279617
ERK1/2phosphorylation
→
down-regulates activity 		SOX10SIGNOR-277821
ERK1/2phosphorylation
→
down-regulates activity 		SOX10SIGNOR-277820