| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN14 | BCAR1 | Tyr128 | SKAQQGLyQVPGPSP | dephosphorylation down-regulates | 22710723 | SIGNOR-197923 |
| SRC | BCAR1 | Tyr128 | SKAQQGLyQVPGPSP | phosphorylation up-regulates activity | 22710723 | SIGNOR-197927 |
| FGFR1 | BCAR1 | Tyr128 | SKAQQGLyQVPGPSP | phosphorylation up-regulates | 11019781 | SIGNOR-82760 |
| FGFR1 | BCAR1 | Tyr128 | SKAQQGLyQVPGPSP | phosphorylation up-regulates | 12601080 | SIGNOR-98488 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN14 | dephosphorylation down-regulates ⊣ | BCAR1 PTyr128 | dephosphorylation up-regulates → | BCAR1 | 22710723 | SIGNOR-197923 |
| SRC | phosphorylation up-regulates → | BCAR1 PTyr128 | phosphorylation up-regulates → | BCAR1 | 22710723 | SIGNOR-197927 |
| FGFR1 | phosphorylation up-regulates → | BCAR1 PTyr128 | phosphorylation up-regulates → | BCAR1 | 11019781 | SIGNOR-82760 |
| FGFR1 | phosphorylation up-regulates → | BCAR1 PTyr128 | phosphorylation up-regulates → | BCAR1 | 12601080 | SIGNOR-98488 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN14 | dephosphorylation down-regulates | BCAR1 | SIGNOR-197923 |
| SRC | phosphorylation → up-regulates activity | BCAR1 | SIGNOR-197927 |
| FGFR1 | phosphorylation → up-regulates | BCAR1 | SIGNOR-82760 |
| FGFR1 | phosphorylation → up-regulates | BCAR1 | SIGNOR-98488 |
