| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PINK1 | PTEN | Ser179 | RRYVYYYsYLLKNHL | phosphorylation down-regulates activity | 37940999 | SIGNOR-277915 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PINK1 | phosphorylation up-regulates → | PTEN PSer179 | phosphorylation down-regulates ⊣ | PTEN | 37940999 | SIGNOR-277915 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PINK1 | phosphorylation → down-regulates activity | PTEN | SIGNOR-277915 |