Entity Details

Name STK11_Thr382
ID P60484
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK2A1PTENThr382DHYRYSDtTDSDPENphosphorylation
down-regulates activity		21779440SIGNOR-89826
STK11PTENThr382DHYRYSDtTDSDPENphosphorylation
down-regulates activity		21779440SIGNOR-161122
PTENPTENThr382DHYRYSDtTDSDPENdephosphorylation
up-regulates activity		22413754SIGNOR-248546
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK2A1phosphorylation
up-regulates
→
PTEN
PThr382		phosphorylation
down-regulates
⊣		PTEN21779440SIGNOR-89826
STK11phosphorylation
up-regulates
→
PTEN
PThr382		phosphorylation
down-regulates
⊣		PTEN21779440SIGNOR-161122
PTENdephosphorylation
down-regulates
⊣
PTEN
PThr382		dephosphorylation
down-regulates
⊣		PTEN22413754SIGNOR-248546
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK2A1phosphorylation
→
down-regulates activity 		PTENSIGNOR-89826
STK11phosphorylation
→
down-regulates activity 		PTENSIGNOR-161122
PTENdephosphorylation
→
up-regulates activity 		PTENSIGNOR-248546