Entity Details

Name STK11_Thr383
ID P60484
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTENPTENThr383HYRYSDTtDSDPENEdephosphorylation
up-regulates activity		22413754SIGNOR-248545
CSNK2A1PTENThr383HYRYSDTtDSDPENEphosphorylation
down-regulates activity		21779440SIGNOR-89830
STK11PTENThr383HYRYSDTtDSDPENEphosphorylation
down-regulates activity		18321849SIGNOR-161126
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTENdephosphorylation
down-regulates
⊣
PTEN
PThr383		dephosphorylation
down-regulates
⊣		PTEN22413754SIGNOR-248545
CSNK2A1phosphorylation
up-regulates
→
PTEN
PThr383		phosphorylation
down-regulates
⊣		PTEN21779440SIGNOR-89830
STK11phosphorylation
up-regulates
→
PTEN
PThr383		phosphorylation
down-regulates
⊣		PTEN18321849SIGNOR-161126
Regulator Mechanism/Effect Target SIGNOR-ID
PTENdephosphorylation
→
up-regulates activity 		PTENSIGNOR-248545
CSNK2A1phosphorylation
→
down-regulates activity 		PTENSIGNOR-89830
STK11phosphorylation
→
down-regulates activity 		PTENSIGNOR-161126